| 翻白草化学成分研究 |
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| 引用本文： | 薛培凤,尹婷,梁鸿,赵玉英.翻白草化学成分研究[J].中国药学杂志,2005,40(14):1052-1053. |
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| 作者姓名： | 薛培凤 尹婷 梁鸿 赵玉英 |
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| 作者单位： | 北京大学药学院天然药物学系天然药物化学研究室,北京,100083 |
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| 摘 要： | 目的研究翻白草的化学成分方法应用硅胶、大孔吸附树脂R-A,Sephadex LH-20柱色谱进行分离纯化,根据理化性质和波谱分析对化合物的结构进行鉴定。结果从翻白草全草中分离并鉴定了6个化合物,分别为乌苏酸(Ⅰ)、2α,3β-二羟基-乌苏-12-烯-28-酸(Ⅱ)、euscaphic acid(Ⅲ)、委陵菜酸(Ⅳ)、胡萝卜苷(Ⅴ)、β-谷甾醇(Ⅵ) 结论所有化合物均为首次从该种植物中得到。
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| 关 键 词： | 翻白草 三萜 甾醇 |
| 文章编号： | 1001-2494（2005）14-1052-03 |
| 收稿时间： | 2005-01-26 |
| 修稿时间： | 2005-01-26 |
Study on chemical constituents of Potentilla discolor |
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| XUE Pei-feng,YIN Ting,LIANG Hong,ZHAO Yu-ying.Study on chemical constituents of Potentilla discolor[J].Chinese Pharmaceutical Journal,2005,40(14):1052-1053. |
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| Authors: | XUE Pei-feng YIN Ting LIANG Hong ZHAO Yu-ying |
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| Institution: | Department of Natural Medicines， School of Pharmaceutical Science， Peking University， Beijing 100083， China |
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| Abstract: | OBJECTIVE To study the chemical constituents of the whole plant of Potentilla discolor Bunge. METHODS Repeated chro-matographies of silicagel column, highly porous resin R-A,and Sephadex LH - 20 were employed for the isolation and purification. The structures of the constituents were elucidated by the spectral analysis.RESULTS Six compounds were identified as ursolic acid (Ⅰ) ,2α,3β-di-hydroxyl-urs-12-en-28-oic acid(Ⅱ), euscaphic acid(Ⅲ), tormentic acid(Ⅳ),β-sitosteriol-3-O-β-D-glucopyranoside(Ⅴ) and β-sitosterol (Ⅵ) .CONCLUSION All compounds are isolated from this plant for the first time. |
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| Keywords: | Potentilla discolor Bunge triterpenes sterols |
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