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| 祁州漏芦根中的三萜成分 | |
| 引用本文： | 张永红,张建钢,谢捷明,陈革林,程东亮.祁州漏芦根中的三萜成分[J].中国中药杂志,2005,30(23):1833-1836. |
| 作者姓名： | 张永红 张建钢 谢捷明 陈革林 程东亮 |
| 作者单位： | 1. 福建医科大学,药学院,福建,福州,350004 2. 兰州大学,药学院,甘肃,兰州,730000 3. 兰州大学,应用有机化学国家重点实验室,甘肃,兰州,730000 |
| 基金项目： | 国家自然科学基金项目（29772010）;福建省教育厅项目（K04054） |
| 摘 要： | 目的:研究祁州漏芦Rhaponticum uniflorum根中的化学成分。方法:采用硅胶及Sephadex LH-20柱色谱进行分离纯化,通过理化性质和光谱分析鉴定结构。结果:从中分离得到了5个三萜类化合物,分别鉴定为乌索酸(1),3-氧-19α-羟基乌索-12-烯-28-酸(2),坡模堤酸(3),arjunic acid(4)和tormentic acid(5)。结论:以上化合物1~5均为首次从该属植物中分得。 |
| 关 键 词： | 祁州漏芦 菊科 三萜 |
| 文章编号： | 1001-5302（2005）23-1833-04 |
| 收稿时间： | 2004-12-10 |
| 修稿时间： | 2004-12-10 |
Triterpenes from root of Rhaponticum uniflorum |
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| ZHANG Yong-hong;ZHANG Jian-gang;XIE Jie-ming;CHEN Ge-lin;CHENG Dong-liang.Triterpenes from root of Rhaponticum uniflorum[J].China Journal of Chinese Materia Medica,2005,30(23):1833-1836. | |
| Authors: | ZHANG Yong-hong;ZHANG Jian-gang;XIE Jie-ming;CHEN Ge-lin;CHENG Dong-liang |
| Institution: | 1. School of Pharmacy, Fujian Medical University, Fuzhou 350004, China ; 2. School of Pharmacy, Lanzhou University, hmzhou 730000, China; 3. National Laboratory of Applied Organic Chemistry, Lanzhou Univershy, Lanzhou 730000, China |
| Abstract: | OBJECTIVE: To study the chemical constituents of the root of Rhaponticum uniflorum. METHOD: Separation and purification were performed on silica gel and Sephadex LH-20 column chromatography. Their structure were elucidated on the basis of physicochemical and spectral analysis. RESULT: Five triterpenoid compounds were isolated and identified as ursolic acid (1), 3-oxo-19alpha-hydroxyurs-12-en-28-oic acid (2), pomolic acid (3), arjunic acid (4) and tormentic acid (5), respectively. CONCLUSION: Compounds 1 approximately 5 were isolated from the genus Rhaponticum for the first time. |
| Keywords: | Rhaponticum uniflorum Compositae triterpenes |
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