通脉益智胶囊治疗血管性痴呆的临床观察

目的：观察通脉益智胶囊对血管性痴呆患者认知功能、临床证候及实验室检查的影响。方法：采用口服通脉益智胶囊治疗血管性痴呆患者30例，并设对照组（口服喜德镇片）20例，观察患者治疗前后变化。结果：通脉益智胶囊治疗组总有效率为70．67％，对照组为70．00％，两组经统计学分析差异无显著性。结论：通脉益智胶囊和喜德镇均有较好的扩张血管、增加脑血流量降低机体高凝状态、增强清除自由基能力等功能。

Clinical Observation on Effect of Tongmai Yizhi Capsule in Treating Vascular Dementia

Objective: To observe the effect of Tongmai Yizhi capsule (TMYZC) on learning in patients of vascular dementia (VD). Methods: Thirty patients of VD were treated by oral administration of TMYZC, the changes in them before and after treatment were observed and compared with those in the 20 patients treated with hydergine as control. Results: The total effective rate in the TMYZC treated group was 70.67% while that in the control group was 70.00%, the difference between the two groups was insignificant. Conclusion: Both TMYZC and hydergine have the effects of dilating blood vessels, increasing the cerebral blood flow, lowering the hyper-coagulative status and improving the free radical scavenging capability of patients.