| 艾灸抗炎作用及对炎症介质影响的实验研究 |
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| 引用本文： | 唐照亮,宋小鸽.艾灸抗炎作用及对炎症介质影响的实验研究[J].针刺研究,1999,24(3):212-215. |
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| 作者姓名： | 唐照亮 宋小鸽 |
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| 作者单位： | 安微中医学院针灸经络研究所!合肥230038(唐照亮,宋小鸽,候正明,陈全珠,章复清,袁静),安微中医学院针灸经络研究所!(朱舜丽) |
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| 基金项目： | 国家自然科学基金!（No．39670903） |
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| 摘 要： | 本实验观察了艾灸“肾俞”穴区对佐剂性关节炎大鼠的抗炎作用,分析了灸治对主要几种炎症介质的影响。结果表明,灸疗能减轻大鼠中后期的炎症反应,能消肿散瘀,防治或减轻其迟发性多发性关节炎,有明显的抗炎作用。对炎症介质的观察表明,灸治能降低炎症化学介质（Ｈｍ、５－ＴＨ）和炎性细胞因子（ＴＮＦ、 ＩＬ－１β）的含量,与炎症对照组比较,差异显著（Ｐ＜ ０．０５或 Ｐ＜０．０１）。表明灸疗能抑制炎性组织细胞合成与释放炎症化学介质和炎性细胞因子,减缓或中止炎症反应,起到了抗炎抑炎作用。
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| 关 键 词： | 艾灸 佐剂性关节炎 抗炎 炎症介质 细胞因子 |
Effects of Moxibustion on Experimental Inflammation Model and Inflammatory Mediators in Rats |
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| Abstract: | The model of adjuvant arthritis in the rat was established to investigate the anti-inflammatory effects of the moxibustion at "Shenshu"(BL 23)point and its effects on several inflammatory mediators. The result showed that the moxibustion alleviated the inflammatory reaction and significantly reduced the level of the chemical inflammatory mediator(Hm, 5-HT) and the inflammatory cytokine (TNF, IL-1β) (P < 0. 05 or P < 0. 01. comparing with control group). It indicates that the therapy can inhibit the formation and release of the chemical inflammation mediator and inflammatory cytokine in inflammatory cells, alleviate or stop inflammatory reaction, dissipate blood stasis and relieve the swelling, prevent and cure delayed polyarthritis, and thus it can produce an anti-inflammatory effect. |
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