| 软骨组织工程的研究进展 |
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| 引用本文： | 张莹莹,周广东,曹谊林.软骨组织工程的研究进展[J].组织工程与重建外科,2011(6):340-343. |
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| 作者姓名： | 张莹莹 周广东 曹谊林 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院整复外科 |
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| 基金项目： | 国家自然科学基金项目(30772264,50830105,30973131);上海市曙光计划项目(08SG19);上海市启明星计划跟踪项目(09QH1401600) |
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| 摘 要： | 目前，软骨组织工程已在基础研究方面取得了令人瞩目的成果，并在临床应用方面进行了初步尝试，为I临床软骨缺损的修复提供了新的思路与途径，已经成为该领域主要的研究方向，但其大规模临床应用尚存在诸多困难。现结合近年的研究成果，就组织工程化软骨的种子细胞、生物支架材料、体内外构建以及临床应用等方面进行综述。
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| 关 键 词： | 软骨组织工程 种子细胞 支架材料 体内外构建 临床修复 |
Research Progress of Cartilage Tissue Engineering |
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| Authors: | ZHANG Yingying ZHOU Guangdong CAO Yilin |
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| Institution: | .Department of Plastic and Reconstructive Surgery,Shanghai Ninth People′s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China |
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| Abstract: | At present, cartilage tissue engineering has made resounding achievements in basic research, and has been applied to preliminary clinical practice which showed a promising approach for repair of cartilage defect. However, as to clinical application in the future, many difficulties remained. This review covered both the current situation of the research development in cartilage tissue engineering （seeding cells, bio-scaffolds, in vitro and in vivo construction） and the obstacles of its clinical application. |
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| Keywords: | Cartilage tissue engineering Seeding cells Bio-scaffolds In vitro and in vivo construction Clinical repair |
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