原发性高血压伴高尿酸血症与冠心病发生的相关性研究

目的:探讨在原发性高血压病患者中,高尿酸血症与冠心病的关系。方法:观察121例原发性高血压病及原发性高血压病伴冠心病患者血尿酸浓度及总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇等冠心病危险因素,用冠状动脉造影方法确诊冠心病。结果:高血压伴冠心病组患者血尿酸浓度及高尿酸血症发生率高于单纯高血压组;血尿酸浓度越高,冠状动脉病变支数越多。结论:高尿酸血症是冠心病的一个危险因素,有必要监测及及时干预高血压患者的血尿酸浓度。

The Relationship between Hyperuricemia and Coronary Artery Disease in Patients with Hypertension

Objective:To investigate the relationship between hyperuricemia and coronary artery disease in patients with hypertension.Methods:A total of 121 patients were recruited in the study,all subjects were divided into hypertension group and hypertension with coronary artery disease group.Serum levels of uric acid,total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and other risk factors for cardiovascular disease were determined,and coronary artery disease was diagnosed by using coronary angiography.Results:The serum levels of uric acid and incidence rate of hyperuricemia were significantly higher in hypertension with coronary artery disease group,and the augmented serum levels of uric acid was accompanied by more and more atherosclerotic vessels involved in.Conclusion:Hyperuricemia is a risk factor for coronary artery disease,and it is essential to monitor the serum levels of uric acid and heal hyperuricemia in hypertension.