扩散加权成像对前列腺外周带癌的诊断

目的探讨扩散加权成像（DWI）在前列腺外周带癌诊断中的价值。方法分别对21例前列腺癌患者、28例前列腺增生（BPH）患者和15名健康志愿者进行前列腺DWI扫描，分析三者的DWI图、表观扩散系数（ADC）图的信号表现，测量癌灶、前列腺增生、正常前列腺外周带的ADC值。所有前列腺癌及前列腺增生病例均以手术或穿刺活检病理诊断为标准。结果DWI上前列腺癌灶表现为高信号影，前列腺增生结节呈稍高信号且信号较混杂，正常前列腺外周带呈稍低信号。前列腺癌灶平均ADC值0．98×10^-3mm^2／s，前列腺增生结节平均ADC值1．32×10^-3mm^2／s；志愿者前列腺外周带平均ADC值2．14×10^-3mm^2／s。结论前列腺癌灶、前列腺增生结节、正常前列腺外周带在DWI图像上信号有较大差别，前列腺癌灶信号较高。前列腺癌灶的ADC值低于正常前列腺外周带及前列腺增生结节。DWI是诊断前列腺外周带癌的依据之一。

Value of diffusion-weighted imaging in the diagnosis of prostate carcinoma

Objective To explore the diagnostic value of diffusion-weighted imaging （DWI） and apparent diffusion coefficient （ADC） in prostate carcinoma （PCa）. Methods Forty-nine patients with histologically confirmed PCa （21） or benign prostatic hyperplasia （BPH, 28） and 15 healthy volunteers underwent DWI. The DWI and ADC characteristics were analyzed. Results PCa showed very high signal intensity on DWI. The signal intensity of BPH was more heterogeneous and lower than whereas the signal intensity of normal peripheral zone was even lower and homogeneous. The mean ADC values of PCa, BPH and normal peripheral zone were 0.98 x 10-3mm2/s, 1.32 x 10-3mm2/s and 2.14 x 10-3mm2/s, respectively. Conclusions PCa has very high DWI signal intensity with significantly lower ADC values than BPH and normal oerioheral zone allowin~ diagnosis of carcinoma.