| 骨质疏松与骨关节炎患者松质骨的显微结构 |
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| 引用本文： | 李展春,程光齐,张自明,戴力扬.骨质疏松与骨关节炎患者松质骨的显微结构[J].国际病理科学与临床杂志,2011,31(1). |
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| 作者姓名： | 李展春 程光齐 张自明 戴力扬 |
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| 作者单位： | 1. 上海交通大学医学院,附属仁济医院骨科,上海,200127
2. 上海交通大学医学院,附属新华医院骨科,上海,200092 |
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| 摘 要： | 目的:通过显微计算机断层扫描(micro-computed tomography,Micro-CT)检测股骨头松质骨显微结构,研究骨质疏松与骨关节炎的关系。方法:绝经后妇女骨质疏松性股骨颈骨折和原发性髋关节骨关节炎患者各20名,以Micro-CT扫描检测股骨头软骨下松质骨标本,对2组患者的松质骨显微结构参数进行比较。结果:骨质疏松与骨关节炎松质骨显微结构参数:骨体积分数(bone volume fraction,BV/TV)、骨表面积体积比(bone surface/bone volume,BS/BV)、骨小梁厚度(trabecular thickness,Tb.Th)、骨小梁间距(trabecular separation,Tb.Sp)、结构模型指数(structure model index,SMI)、连接密度(connectivity density,Conn.D)比较差异有统计学意义,BV/TV,SMI与Tb.N,TbTh,BS/BV,Tb.Sp呈相关关系。结论:骨质疏松与骨关节炎的显微结构存在差异,这些差异可能导致相反的骨缺陷;BV/TV,SMI是评价显微结构参数的2个重要指标。
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| 关 键 词： | 骨质疏松 骨关节炎 显微结构 显微计算机断层扫描 |
Microstructure of the trabecular bone from osteoarthritis and osteoporosis patients |
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| LI Zhanchun,CHENG Guangqi,ZHANG Ziming,DAI Liyang.Microstructure of the trabecular bone from osteoarthritis and osteoporosis patients[J].Journal of International Pathology and Clinical Medicine,2011,31(1). |
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| Authors: | LI Zhanchun CHENG Guangqi ZHANG Ziming DAI Liyang |
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| Institution: | LI Zhanchun1,CHENG Guangqi1,ZHANG Ziming2,DAI Liyang2(1.Department of Orthopedics,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,2.Department of Orthopedics,Xinhua Hospital,Shanghai 200092,China) |
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| Abstract: | Objective To investigate relation between osteoarthritis(OA) and osteoporosis(OP) by comparing the structure of trabecular bone from femoral heads.Methods The trabecular bone specimens of femoral heads were taken from 40 postmenopausal women(OA,n=20;OP,n=20).The microstructural parameters of the trabecular bone specimens were measured by Micro-CT.Results Significant differences in bone volume fraction(BV/TV),bone surface/bone volume(BS/BV),trabecular thickness(Tb.Th),trabecular separation(Tb.Sp),structure m... |
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| Keywords: | osteoarthritis osteoporosis microstructure micro-computed tomography |
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