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从五脏论治小儿便秘
引用本文:万莉萍,姜之炎.从五脏论治小儿便秘[J].天津中医药大学学报,2020,39(1):38-40.
作者姓名:万莉萍  姜之炎
作者单位:天津中医药大学第一附属医院肿瘤科, 天津 300381,天津中医药大学第二附属医院, 天津 300250,天津中医药大学第一附属医院肿瘤科, 天津 300381,天津中医药大学第一附属医院肿瘤科, 天津 300381,天津中医药大学第一附属医院肿瘤科, 天津 300381
基金项目:天津市卫生和计划生育委员会中医药重点领域科研课题(2017003)。
摘    要:从中医五脏辨证理论对儿童便秘的病因病机及治法方药进行总结,发现儿童便秘与心肝脾肺肾五脏关系密切,通过临床脏腑辨证选方用药可减轻患儿便秘症状。从五脏辨证施治儿童便秘,在改善临床症状方面作用明显。

关 键 词:五脏  儿童便秘  中医药
收稿时间:2019/10/3 0:00:00

Treatment from five-viscera correlation theory for pediatric constipation
WAN Liping and JIANG Zhiyan.Treatment from five-viscera correlation theory for pediatric constipation[J].Journal of Tianjin University of Traditonal Chinese Medicine,2020,39(1):38-40.
Authors:WAN Liping and JIANG Zhiyan
Institution:Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China,The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China,Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China,Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China and Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
Abstract:Objective] To observe the effect of Xiaoyan Decoction combined with chemotherapy on peripheral blood vascular endothelial growth factor (VEGF) in patients with advanced non-small cell lung cancer (NSCLC) and its clinical efficacy.Methods] The 60 patients with advanced NSCLC were randomly divided into two groups:the observation group (30 cases) received GP regimen chemotherapy combined with oral Xiaoyan Decoction;the control group (30 cases) received chemotherapy alone. After two cycles of chemotherapy,the recent observable curative effect,improvement of symptoms,improvement of quality of life,changes of serum levels of vascular endothelial growth factor and toxic and side effects were observed.Results] Xiaoyan Decoction combined with chemotherapy was superior to chemotherapy alone in stabilizing tumors,improving patients'' chi-square scores and improving patients'' quality of life. The difference between the two groups was statistically significant. Moreover,Xiaoyan Decoction combined with chemotherapy could significantly reduce the serum level of vascular endothelial growth factor,which had significant difference compared with chemotherapy alone. In terms of drug safety,Xiaoyan Decoction could significantly reduce the toxic side effects of chemotherapy,especially in the reduction of leukopenia,hemoglobin and other hemotoxicity improvement has a good clinical effect.Conclusion] Xiaoyan Decoction combined with chemotherapy can alleviate the clinical symptoms of advanced NSCLC,improve KPS score,stabilize the lesion,inhibit the expression of vascular endothelial growth factor,alleviate the toxic side effects of hematopoietic system and improve the quality of life of patients.
Keywords:Xiaoyan Decoction  advanced NSCLC  chemotherapy  angiogenesis  VEGF
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