| 咖啡酸锗对小鼠子宫颈癌14号的抑制作用 |
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| 引用本文： | 陈晓东,叶连宝,黄桂林,肖纯.咖啡酸锗对小鼠子宫颈癌14号的抑制作用[J].中国药业,2006,15(1):29-29. |
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| 作者姓名： | 陈晓东 叶连宝 黄桂林 肖纯 |
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| 作者单位： | 江西中医学院,江西,南昌,330006 |
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| 摘 要： | 目的:观察咖啡酸锗对小鼠子宫颈癌14号(U14)的作用。方法:以无菌生理盐水按1∶3稀释,调整细胞数约为2.08×109个/L,于每只小鼠右肢皮下接种0.2mLU14,以咖啡酸锗高、中、低3个剂量连续给药10d,以生理盐水组为模型对照组,计算各剂量组对U14的抑制率。结果:咖啡酸锗高、中剂量对U14有较好的抑制率,低剂量也有一定的抑制作用,且给药前后小鼠体重明显增加。结论:咖啡酸锗对小鼠U14有抑制作用,且毒性很小。
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| 关 键 词： | 咖啡酸锗 抗肿瘤 子宫颈癌14号 抑制 |
| 文章编号： | 1006-4931(2006)01-0029-01 |
| 收稿时间： | 03 2 2005 12:00AM |
| 修稿时间： | 05 8 2005 12:00AM |
The Inhibitory Effect of Germanium Caffeic Acid on the Tumor U14 |
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| Chen Xiaodong,Ye Lianbao,Huang Guilin,Xiao Chun.The Inhibitory Effect of Germanium Caffeic Acid on the Tumor U14[J].China Pharmaceuticals,2006,15(1):29-29. |
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| Authors: | Chen Xiaodong Ye Lianbao Huang Guilin Xiao Chun |
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| Abstract: | Objective:To observe the inhibitory effect of germanium caffeic acid on the tumor U14.Methods:The germanium caffeic acid was administered constantly for 10 d with high,middle,low dose.Results:The group administered high and middle dose had better inhibitory effect and the group with low dose had a little hibitory effect.Moreover,the mice's body weight increased evidencely during administering drug.Conclusion:Germanium caffeic acid has strongly inhibitory effect and low toxicity. |
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| Keywords: | germanium caffeic acid anti - tumor U14 inhibit |
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