高血压患者心肌缺血与颈动脉粥样硬化的相关性研究

目的探讨高血压患者的心肌缺血与颈动脉粥样硬化之间的相关性。方法收集2005年5月至2008年9月在本院经查冠脉CTA排除冠心病的高血压患者共85例,首先根据平板运动负荷试验的结果将资料分为有无心肌缺血2组,与其影响因素间行单因素及多因素分析;然后再分析其与颈总动脉IMT及斑块的Crouse评分、室间隔及左室壁的厚度之间的相关性;最后建立ROC曲线评估颈总动脉的IMT及斑块的Crouse评分预测心肌有无缺血的价值。结果颈动脉斑块形成被发现是高血压患者心肌缺血的主要危险因素(OR=4.982,P=0.004),伴有颈动脉斑块形成的高血压患者其心肌缺血的发生率明显高于颈动脉无斑块形成的高血压患者(χ2=9.317,P=0.002);高血压患者的心肌缺血与室间隔及左室壁的厚度呈正相关(r=0.362,P=0.001;r=0.298,P=0.009),颈总动脉的IMT与室间隔厚度呈正相关(r=0.231,P=0.045);以Crouse评分预测高血压患者心肌有无缺血的ROC曲线下面积AUC为0.726±0.061,P=0.001;IMT的ROC曲线下面积AUC为0.682±0.061,P=0.006。结论颈动脉斑块形成...

Correlation between myocardial ischemia and carotid atherosclerosis in hypertensive patients

Objective To analyze the correlation between myocardial ischemia and carotid atherosclerosis in hypertensive patients.Methods The clinical data were collected from 85 hospitalized hypertensive patients admitted between May 2005 and September 2008 without the complication of coronary artery disease as confirmed by cardiac computed tomographic angiography(CTA).According to the results of treadmill exercise test,the patients were divided myocardial ischemia group and ischemia-free group.Univariate and multivar...