| Clinical Study of Gushen Tablet(固肾片)in Reducing Children's Nephrotic Syndrome Relapse |
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| 引用本文： | 云鹰,高雅,马玉宏,刘望乐,赵蒙,高智铭.Clinical Study of Gushen Tablet(固肾片)in Reducing Children''''s Nephrotic Syndrome Relapse[J].Chinese Journal of Integrated Traditional and Western Medicine,2003,9(3). |
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| 作者姓名： | 云鹰 高雅 马玉宏 刘望乐 赵蒙 高智铭 |
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| 作者单位： | The First Affiliatea Hospital，Henan College of TCM，Zhengzhou 450000，Henan Academy of TCM，The First Affiliated Hospital，Henan College of TCM，Zhengzhou 450000，Hospital of Henan TCM College，Zhengzhou City Children Hospital，The First Affiliatea Hospital，Henan College of TCM，Zhengzhou 450000 |
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| 基金项目： | The item was supported by the Science and Technology Department of Henan Province (No. 941200528) |
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| 摘 要： | ObjeCtive:To explore the effect of Gushen tablet(固肾片,GST)In reducing the relapseof chidren’s nephrotic syndrome and the possible mechanism of drugs used.Methods:Fifty Children withprimary nephrotic syndrome who had been induced and alleviated with regular glucocorticoid(GC)wererandomly divided into two groups:the GST group used GST and standard middle-long term course of GC,and the control group adopted standard middle-long term course of GC and immunoinhibitory or immuno-modulatory agents for treatment.The 0.5,1 and 2 years after the treatment the relapse episodes,time forurinary protein negative conversion after relapse,the episodes of patient’s infection and relapse after infec-tion were evaluated.Before and after treatment the plasma cortisol and T lymphocyte subpopulation weredetermined.Results:The relapse rate of GST group:the rates after 0.5,1,2 years were 20.0％,30.0％and 40.9％,and the frequent relapse rate were 0,6.7％ and 9.2％ respectively,which were lower thanthose of control group(60.
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Clinical Study of Gushen Tablet(固肾片) in Reducing Children's Nephrotic Syndrome Relapse |
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| Authors: | YUN Ying GAO Ya MA Yu-hong
LIU Wang-le ZHAO Meng and GAO Zhi-ming The First Affiliated Hospital Henan College of TCM Zhengzhou |
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| Abstract: | |
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| Keywords: | ushen tablet children nephrotic syndrome relapse adrenocortical function T lymphocyte subpopulation |
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