| 流行性出血热患者血清超氧化物歧化酶、丙二醛含量变化与其发病机理的关系 |
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| 引用本文： | 臧国庆,张国统,吴修斌.流行性出血热患者血清超氧化物歧化酶、丙二醛含量变化与其发病机理的关系[J].蚌埠医学院学报,1992(3). |
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| 作者姓名： | 臧国庆 张国统 吴修斌 |
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| 作者单位： | 西安医科大学第二附属医院传染病科，西安医科大学第二附属医院传染病科，西安医科大学第二附属医院传染病科 研究生 蚌埠医学院附院传染科，导师，导师 |
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| 摘 要： | 本文测定32例健康人和101例流行性出血热(EHF)患者血清超氧化物歧化酶(SOD),丙二醛(MDA)的含量。结果表明EHF患者血清SOD、MDA含量均高于健康对照组,以低血压少尿期升高最为明显。测定中还发现SOD、MDA含量升高与病情变化程度有一定关系。作者认为自由基参与了EHF的发病过程。研究EHF与自由基的关系有助于进一步阐明EHF的发病机理并为其临床治疗提供一定的参考价值。
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| 关 键 词： | 流行性出血热 超氧化物歧化酶 丙二醛 自由基 血清 发病机理 |
THE RELATIONSHIP BETWEEN SERUM SOD-MDA LEVELS AND PATHOGENESIS IN EPIDEMIC HEMORRHAGIC FEVER |
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| Zhang Guoqing.THE RELATIONSHIP BETWEEN SERUM SOD-MDA LEVELS AND PATHOGENESIS IN EPIDEMIC HEMORRHAGIC FEVER[J].Journal of Bengbu Medical College,1992(3). |
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| Authors: | Zhang Guoqing |
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| Abstract: | The superoxide dismutase ( SOD ) and malondialdehyde ( MDA ) levels in serum were measured in 32 normal controls and in 101 patients with epidemic hemo rhagic fever ( EHF ) .The results demonstrated that SOD-MDA levels in serum in every phase of the disease were higher than the normal controls. The severer the patients were, the higher the SOD and MDA levels in serum.The authors believe that free radicals have a relationship to the pathogenesis of EHF. The study on the relationship between free radicals and EHF not only helps to explain the pathogenesis of EHF but also benifits the treatment of the disease. |
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| Keywords: | epidemic hemorrhagic fever ( EHF ) free radical superoxide dismutase ( SOD ) malondialdehyde ( MDA ) |
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