心肌酶检测在婴幼儿呼吸道合胞病毒肺炎中的价值评估

目的探讨心肌酶检测在婴幼儿RSV肺炎的价值评估。方法选取该院2011年1月—2014年6月住院治疗的婴幼儿肺炎中RSV滴度阳性的患儿180例,同时选取儿童保健门诊64例正常婴幼儿作为对照组,检测他们的心肌酶（乳酸脱氢酶LDH、α-羟丁酸脱氢酶HBDH、磷酸肌酸激酶CK、磷酸肌酸激酶同工酶CK-MB）并进行比较,同时根据病情轻重把RSV肺炎组分为轻症组和重症组,比较两组心肌酶的活性。结果 RSV肺炎组的心肌酶活性均显著高于对照组（P〈0.05）,RSV肺炎轻症组和重症组的心肌酶活性无明显统计学意义（P〉0.05）。结论婴幼儿RSV肺炎患儿存在血清心肌酶活性的增高,但不能据此来诊断存在心肌损害,故临床价值不高,而且不能依据心肌酶的高低来评价RSV肺炎病情的轻重程度。

Valuation Cardiac Enzymes Detected In Infants With Respiratory Syncytial Virus Pneumonia

Objective To investigate the cardiac enzymes detect RSV in infants valuation pneumonia. Methods In our hospital in2011 has pneumonia in hospitalized infants RSV titer positive children 180 cases, while 64 cases selected child health clinic as a control group of normal infants, testing their cardiac enzymes（lactate dehydrogenase LDH, α- hydroxybutyrate dehydrogenase α-HBDH, creatine kinase CK, creatine kinase isoenzyme CK-MB） and compared, while according to the severity of the RSV pneumonia group was divided into mild group and severe group were compared myocardial enzyme activity. Results The enzyme activity in RSV pneumonia group were significantly higher（P〈0.05）, enzyme activity in mild group and severe RSV pneumonia group had no statistically significant（P〉0.05）. Conclusion RSV pneumonia in infants with elevated serum enzyme activity in the presence, but not pursuant to diagnose the presence of myocardial damage, so the clinical value is not high, and can not be based on the level of cardiac enzymes to evaluate the degree of severity of RSV disease pneumonia .