| 斑马鱼分子遗传位标及多态性研究进展 |
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| 引用本文： | 赵莹,沈志敏,刘雄伟,魏晓锋,胡建华.斑马鱼分子遗传位标及多态性研究进展[J].实验动物与比较医学,2011,31(2):147-152. |
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| 作者姓名： | 赵莹 沈志敏 刘雄伟 魏晓锋 胡建华 |
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| 作者单位： | 1. 上海实验动物研究中心,上海,201203;上海西普尔-必凯实验动物有限公司,上海,201203
2. 上海实验动物研究中心,上海,201203;上海市实验动物质量监督检验站,上海,201203 |
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| 基金项目： | 上海市科学技术委员会创新行动计划项目 |
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| 摘 要： | 过去二十年间,分子遗传位标可揭示DNA水平的多态性,在斑马鱼的遗传研究中所占比重越来越大.本文介绍分子遗传位标及斑马鱼遗传图谱,探讨这些遗传位标使用时的优缺点,展示斑马鱼品系的多态性.
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| 关 键 词： | 分子遗传位标 RAPD SSCP STR SNP 多态性 斑马鱼 |
Progress on Molecular Markers for Zebrafish and Polymorphism in Zebrafish Strains |
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| ZHAO Ying,SHEN Zhi-min,LIU Xiong-wei,WEI Xiao-feng,HU Jian-hua.Progress on Molecular Markers for Zebrafish and Polymorphism in Zebrafish Strains[J].Laboratory Animal and Comparative Medicine,2011,31(2):147-152. |
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| Authors: | ZHAO Ying SHEN Zhi-min LIU Xiong-wei WEI Xiao-feng HU Jian-hua |
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| Institution: | 1. Shanghai Laboratory Animal Research Center, Shanghai 201203, China; 2. Sino-British SIPPR /BK Lab.Animal LTD, CO, Shanghai 201203, China; 3. Shanghai Quality Monitoning Center for Lab.Animals, Shanghai 201203, China) |
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| Abstract: | During the last twenty years, the use of molecular markers, revealing polymorphism at the DNA level, has been playing an increasing part in zebrafish genetics studies. In this review, the molecular markers and genetic maps for zebrafish was introduced, the advantages and disadvantages of using these markers was discussed, and the polymorphism in zebrafish strains was described. |
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| Keywords: | RAPD SSCP STR SNP |
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