| 正交试验优选利胆排石胶囊的水煎提取制备工艺 |
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| 引用本文： | 秦龙,李平,李玉民,焦海胜.正交试验优选利胆排石胶囊的水煎提取制备工艺[J].中国药师,2015(5):769-772. |
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| 作者姓名： | 秦龙 李平 李玉民 焦海胜 |
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| 作者单位： | 兰州大学第二医院 兰州 730030；;兰州大学第二医院；甘肃省消化系肿瘤重点试验室;兰州大学第二医院；甘肃省消化系肿瘤重点试验室;兰州大学第二医院 |
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| 基金项目： | 甘肃省科技计划资助项目（编号：145RJZA207），兰州大学中央高校基本科研业务费专项资金资助项目（编号：lzujbky-2013-216），兰州大学第二医院院内中医药科研项目（编号:YJzy2013-38） |
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| 摘 要： | 摘 要 目的： 优选利胆排石胶囊的水煎提取制备工艺。 方法: 以浸膏得率、大黄素含量和大黄酚含量作为考察指标，采用L9(34)正交试验优选利胆排石胶囊最佳水煎提取制备工艺。结果:最佳制备工艺条件为加14倍量的水、煎煮4次、每次2 h。结论: 水煎提取制备工艺易于操作，合理可行。
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| 关 键 词： | 利胆排石胶囊 正交试验 大黄素 大黄酚 |
| 收稿时间： | 2014/11/6 0:00:00 |
| 修稿时间： | 2015/1/11 0:00:00 |
Optimization of Water Extraction Process for Lidan Paishi Capsules by Orthogonal Test |
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| Qin Long,Li Ping,Li Yumin and Jiao Haisheng.Optimization of Water Extraction Process for Lidan Paishi Capsules by Orthogonal Test[J].China Pharmacist,2015(5):769-772. |
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| Authors: | Qin Long Li Ping Li Yumin and Jiao Haisheng |
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| Institution: | The Second Hospital of Lanzhou University, Lanzhou 730030, China;;The Second Hospital of Lanzhou University; Key Laboratory of Digestive System Tumors of Gansu Province;The Second Hospital of Lanzhou University; Key Laboratory of Digestive System Tumors of Gansu Province;The Second Hospital of Lanzhou University |
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| Abstract: | ABSTRACT Objective: To optimize the water extraction process of Lidan Paishi capsules. Methods: The extract yield, emodin content and chrysophanol content were used as the indices, the extraction process of Lidan Paishi capsules was optimized by orthogonal test of L9(34). Results: The optimized water extraction conditions were as follows: adding 14-fold water, and boiling extraction four times with 2 hours for each time. Conclusion:The water extraction process is practicable, reasonable and convenient. |
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| Keywords: | Lidan Paishi capsules Orthogonal test Emodin Chrysophanol |
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