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心肌梗塞患者自然杀伤细胞活性检测
引用本文:李莉,张永珍,侯凤喜,杨俊敏.心肌梗塞患者自然杀伤细胞活性检测[J].郑州大学学报(医学版),1994(2).
作者姓名:李莉  张永珍  侯凤喜  杨俊敏
作者单位:河南医科大学第一附属医院内科
摘    要:用125IUdR释放法测定17例急性心肌梗塞(AMI)后一周内的外周血自然杀伤(NK)细胞活性,并与13例陈旧性心肌梗塞(OMI)及58例正常人对照。结果表明:AMI组NK细胞活性明显低于正常组及OMI组(P<0.01)。AMI组中,梗塞面积广泛者NK细胞活性明显低于梗塞面积局限者(P<0.01)。提示NK细胞活性可作为AMI诊断和预后判断的一个辅助参考指标。

关 键 词:杀伤细胞  活性  心肌梗塞

Reaction of natural killer cell activity to acute myocardial infarction
Li Li,Zhang Yongzhen,Hou Fengxi,Yong Junmin.Reaction of natural killer cell activity to acute myocardial infarction[J].Journal of Zhengzhou University: Med Sci,1994(2).
Authors:Li Li  Zhang Yongzhen  Hou Fengxi  Yong Junmin
Abstract:Natural killer(NK) cell activity was measured in 17 patients in the first week of acute myocardial infarction (AMI) and 13 patients with old myocardial infarction(OMI).58 norma subjects were taken as control,The results showed that NK cell activity in the patients with AMI was depressed when compared with the controls and the patients with OMI (P<0.01).NK cell activity in the patients with extensive AMI was lower than that of the patients with local AMI(P<0.01).The mechanism of the depressed NK cell activity in AMI was discussed.It was suggested that the detection of peripheral blood NK cell activity may have practical significance for the diagnosis of AMI and it may be used as a reference index for the prognosis of AMI.
Keywords:natural killer cells  acute myocardial infarction
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