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东菱迪芙治疗腔隙性脑梗塞后血浆D-二聚体及纤维蛋白原变化
引用本文:唐海英,吴秀英,王芬蝶.东菱迪芙治疗腔隙性脑梗塞后血浆D-二聚体及纤维蛋白原变化[J].军医进修学院学报,2009,30(2):148-149.
作者姓名:唐海英  吴秀英  王芬蝶
作者单位:苏州大学附属第一医院老年科,江苏省苏州市,215006
摘    要:目的:观察东菱迪芙治疗腔隙性脑梗塞患者后血浆D-二聚体(D-Dimer)及纤维蛋白原(FIB)变化。方法:将120例腔梗患者随机分为东菱迪芙组和常规治疗组,各60例。两组均给予神经细胞营养药和常规药物,而东菱迪芙组在第1,第3,第5,第7天加用东菱迪芙治疗;同时设有急性脑梗塞(ACI)组30例,并设正常对照组30例。测定治疗前后血浆D-二聚体和FIB水平。结果:治疗前腔梗患者的血浆D-二聚体水平显著低于急性脑梗塞患者(P〈0.05);东菱迪芙治疗后第7天,D-二聚体水平明显高于治疗前(P〈0.05),FIB明显降低(P〈0.05);第14天,D-二聚体与治疗前差异不显著(P〉0.05)。结论:东菱迪芙使腔隙性脑梗塞患者纤溶活性增强,凝血活性相对减弱,促进微血栓溶解。

关 键 词:东菱迪芙  脑梗塞  D-二聚体  纤维蛋白原

Changes of plasma D-Dimer and fibrinogen in patients with lacunar cerebral infarction after treatment with batroxobin:A comparative analysis
TANG Hai-ying,WU Xiu-ying,WANG Fen-die.Changes of plasma D-Dimer and fibrinogen in patients with lacunar cerebral infarction after treatment with batroxobin:A comparative analysis[J].Academic Journal of Pla Postgraduate Medical School,2009,30(2):148-149.
Authors:TANG Hai-ying  WU Xiu-ying  WANG Fen-die
Institution:Department of Geriatric Medicine;First Affiliated Hospital of Suzhou University;Jiangsu Suzhou 215006;China
Abstract:Objective:To observe the changes of plasma D-Dimer and fibrinogen(FIB)in patients with lacunar cerebral infarction(LI)after treatment with Batroxobin.Methods:A total of 120 patients with LI were randomly divided into Batroxobin treatment group(n=60)and control group(n=60)and treated with neurophic and normal drugs.Batroxobin was used in Batroxobin treatment group on days 1,3,5,and 7.Thirty patients with acute cerebral infarction served as treatment group,30 persons served as control group.Levels of D-Dimer ...
Keywords:batroxobin  brain infarction  D-Dimer  fibrinogen  
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