| 产地鲜切加工与传统加工乌药饮片抗痛经药效比较研究 |
| |
| 引用本文： | 罗云云,康显杰,杨莹,张婷,朱涛,吴瑶,杜伟锋,葛卫红.产地鲜切加工与传统加工乌药饮片抗痛经药效比较研究[J].中草药,2018,49(20):4731-4736. |
| |
| 作者姓名： | 罗云云 康显杰 杨莹 张婷 朱涛 吴瑶 杜伟锋 葛卫红 |
| |
| 作者单位： | 浙江中医药大学药学院;浙江中医药大学中药炮制技术研究中心 |
| |
| 基金项目： | 国家中药标准化项目（ZYBZH-H-ZY-45）;中医药行业科研专项"中药饮片质量保障系统研究（一）"（201507002）;浙江省公益性技术应用研究计划资助项目（2015C33152）;浙江中医药大学重中之重一级学科开放基金项目（2016）;国家自然科学基金预研专项（2016ZG19） |
| |
| 摘 要： | 目的通过痛经模型对产地鲜切加工乌药饮片与传统加工乌药饮片进行药效比较。方法采用雌激素诱导小鼠痛经模型,通过记录小鼠扭体反应及前列腺素E2(PGE2)、前列腺素F2α(PGF2α)、血管加压素(AVP)、β-内啡肽(β-EP)5个指标的变化来比较2种不同加工方式乌药治疗痛经的效果。结果与模型组比较,2种不同加工方式乌药均能明显减少痛经模型小鼠扭体次数(P0.01),降低PGE2、PGF2α、AVP水平(P0.05、0.01),升高β-EP水平(P0.01),但两者相同给药剂量结果差异不显著(P0.05)。结论两种不同加工方法乌药均对痛经模型小鼠起到良好的治疗效果,并且产地鲜切加工乌药与传统加工乌药对痛经模型小鼠的药效强度相当。
|
| 关 键 词： | 乌药 产地鲜切加工 传统加工 痛经 前列腺素E2 前列腺素F2α 血管加压素 β-内啡肽 |
| 收稿时间： | 2018/2/14 0:00:00 |
Comparative study on anti-dysmenorrhea efficacy of habitat fresh-cut processed and traditional processed Linderae Radix |
| |
| LUO Yun-yun,KANG Xian-jie,YANG Ying,ZHANG Ting,ZHU Tao,WU Yao,DU Wei-feng and GE Wei-hong.Comparative study on anti-dysmenorrhea efficacy of habitat fresh-cut processed and traditional processed Linderae Radix[J].Chinese Traditional and Herbal Drugs,2018,49(20):4731-4736. |
| |
| Authors: | LUO Yun-yun KANG Xian-jie YANG Ying ZHANG Ting ZHU Tao WU Yao DU Wei-feng and GE Wei-hong |
| |
| Institution: | College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China,College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China,College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China,College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China,College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China,Research Center of Traditional Chinese Medicine Processing Technology, Zhejiang Chinese Medical University, Hangzhou 311401, China,Research Center of Traditional Chinese Medicine Processing Technology, Zhejiang Chinese Medical University, Hangzhou 311401, China and Research Center of Traditional Chinese Medicine Processing Technology, Zhejiang Chinese Medical University, Hangzhou 311401, China |
| |
| Abstract: | |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
| 点击此处可从《中草药》下载免费的PDF全文 |
|
