| 妊娠期糖尿病患者糖化血清蛋白与尿酸、谷丙转氨酶的相关研究 |
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| 引用本文： | 刘常同,黄萍,岑志恒,周星,陈玉屏,张杏平,傅天珍.妊娠期糖尿病患者糖化血清蛋白与尿酸、谷丙转氨酶的相关研究[J].医学检验与临床,2013,24(2):1-2,21. |
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| 作者姓名： | 刘常同 黄萍 岑志恒 周星 陈玉屏 张杏平 傅天珍 |
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| 作者单位： | 刘常同(广东省南海区第九人民医院,广东佛山,528203)；黄萍(广东省南海区第九人民医院,广东佛山,528203)；岑志恒(广东省南海区第九人民医院,广东佛山,528203)；周星(广东省南海区第九人民医院,广东佛山,528203)；陈玉屏(广东省南海区第九人民医院,广东佛山,528203)；张杏平(广东省南海区第九人民医院,广东佛山,528203)；傅天珍(广东省南海区第九人民医院,广东佛山,528203)； |
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| 基金项目： | 佛山市卫生局医学科研立项,项目(项目编号：2013370) |
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| 摘 要： | 目的：测定妊娠期糖尿病（GDM）患者的糖化血清蛋白（GSP）表达水平并探讨其与血尿酸（UA）和谷丙转氨酶（ALT）的相关性。方法：选择佛山市南海区第九人民医院住院分娩的GDM患者45人作为实验组，并以同期住院分娩的正常孕妇44人作为对照组；血清中GSP浓度测定采用酶联免疫吸附法；UA和ALT测定采用自动生化仪。结果：实验组的GSP、UA和ALT水平均明显高于对照组（P〈0．05）；GDM组GSP与UA和ALT有相关性，相关系数分别为0．523和0．459（P〈0．05）。结论：GSP测定有利于GDM的筛选和早期诊断；UA和ALT也参与了GDM的发生及发展过程。
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| 关 键 词： | 妊娠期糖尿病 糖化血清蛋白 尿酸 谷丙转氨酶 |
Related study of glycosylated serum protein, uric and alanine transaminase in patients with gestational diabetes |
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| LIU Chang-tong,HUANG Ping,CEN Zhi-heng,ZHOU Xing,CHEN Yu-ping,ZHANG Xing-ping,FU Tian-zhen.Related study of glycosylated serum protein, uric and alanine transaminase in patients with gestational diabetes[J].Medical Laboratory Science and Clinics,2013,24(2):1-2,21. |
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| Authors: | LIU Chang-tong HUANG Ping CEN Zhi-heng ZHOU Xing CHEN Yu-ping ZHANG Xing-ping FU Tian-zhen |
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| Institution: | (The ninth people＇s hospital of Nan hal district, Foshan 528203) |
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| Abstract: | Objective ： To detect the expression level of GSP and explore it＇ s relationship with UA and ALT in gestational diabetes mellitus patients. Methods ： 45 gestational diabetes mellitus pregnant women and 44 normal pregnant women at the same time were chosen as the study group and control group from Jiujiang Hospital in Foshan.Serum GSP and UA ,ALT were tested by ELISA and biochemical analyzer,respectively.Results ： GSP,UA and ALT in GDM group were significantly higher than those in normal pregnant group（P〈0.05 ） .There were positive correlations between GSP and UA,ALT in GDM group（r=0.523,P〈0.05; r=0.459 P〈0.05）.Conclusions ： Detection of GSP can be used for screening and early diagnosis of GDM. UA and ALT may participate in the pathogenesis of GDM. |
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| Keywords: | GDM GSP UA ALT |
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