| 脂蛋白残粒RLP-c检测的临床意义 |
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| 引用本文： | 吴培红,刘伟,徐晓萍.脂蛋白残粒RLP-c检测的临床意义[J].上海交通大学学报(医学版),2004,24(8):676-678. |
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| 作者姓名： | 吴培红 刘伟 徐晓萍 |
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| 作者单位： | 上海第二医科大学仁济医院内分泌科，上海第二医科大学仁济医院内分泌科，上海第二医科大学仁济医院检验科 上海 200127 |
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| 摘 要： | 目的 探讨脂蛋白残粒RLP-c作为新的脂质指标的临床意义。方法 采用免疫分离法测定正常对照组(NC)、冠心病组(CHD)和2型糖尿病组(T2DM)的RLP-c水平,并比较RLP-c与其他脂质指标的相关性。结果 CHD组和T2DM组RLP-c水平明显高于NC组(P<0.01),其水平与甘油三脂(TG)和极低密度脂蛋白胆固醇(VLDL-c)高度相关(P<0.01)。结论 RLP-c可用于对动脉粥样硬化的危险性评估。
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| 关 键 词： | 脂蛋白残粒 RLP-c 动脉粥样硬化 免疫分离法 2型糖尿病 T2DM |
| 文章编号： | 0258-5898(2004)08-0676-03 |
| 修稿时间： | 2004年3月17日 |
Clinical significance of RLP-c examination |
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| WU Pei-hong,XU Xiao-ping,LIU Wei.Clinical significance of RLP-c examination[J].Journal of Shanghai Jiaotong University:Medical Science,2004,24(8):676-678. |
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| Authors: | WU Pei-hong XU Xiao-ping LIU Wei |
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| Abstract: | Objective To investigate the clinical significance of RLP-c, which is now considered as a new athero-genic factor. Methods The serum levels of RLP-c were detected with immunoseparation assay in normal controls ( NC ) , patients of coronary heart disease(CHD) and type 2 diabetes ( T2DM) , and the correlation between RLP-c and other lipid parameters was also examined. Results RLP-c concentrations were significantly higher in CHD and T2DM, comparing to NC respectively ( P < 0. 01 ) , and its level was highly correlated with TG and VLDL (P< 0. 01). Conclusion RLP-c could be considered as a new marker to assess the risk of atherosclerosis. |
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| Keywords: | remnant-like particle triglyceride-rich lipoprotein atherosclerosis immunoseparation assay |
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