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| IL-17在子痫前期患者胎盘组织的表达 | |
| 引用本文： | 廖志琼,甘婷,陈希明,吴爱华,廖德贵,陈盛强,肖国宏,方朝辉.IL-17在子痫前期患者胎盘组织的表达[J].解剖学研究,2012,34(2):96-99. |
| 作者姓名： | 廖志琼 甘婷 陈希明 吴爱华 廖德贵 陈盛强 肖国宏 方朝辉 |
| 作者单位： | 1. 广州医学院第二附属医院,广东广州,510260 2. 广州医学院第三附属医院 3. 广州市番禺区石楼人民医院 |
| 基金项目： | 广东省医学科技项目，番禺区科技项目 |
| 摘 要： | 目的探讨白细胞介素-17(IL-17)与子痫前期发病的关系。方法选取2010年10月至2011年12月在广州医学院第二附属医院和广州医学院第三附属医院产科住院的子痫前期患者30例,其中足月妊娠9例,未足月妊娠21例;选取同期住院分娩的正常足月妊娠孕妇30例为对照组。30例正常晚期妊娠孕妇为对照组。采用免疫组化方法检测两组胎盘组织IL-17表达水平。结果子痫前期组胎盘IL-17表达量较对照组升高(P<0.05)。结论IL-17可能介导了子痫前期的发生。 |
| 关 键 词： | 白细胞介素-17 子痫前期 胎盘 |
Expression of iuterleukin-17 in placenta of patients with preeclampsia |
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| LIAO Zhi-qiong , GAN Ting , CHEN Xi-ming , WU Yai-hua , LIAO De-gui , CHEN Sheng-qiang , XIAO Guo-huan , FANG Zhao-hui.Expression of iuterleukin-17 in placenta of patients with preeclampsia[J].Anatomy Research,2012,34(2):96-99. | |
| Authors: | LIAO Zhi-qiong GAN Ting CHEN Xi-ming WU Yai-hua LIAO De-gui CHEN Sheng-qiang XIAO Guo-huan FANG Zhao-hui |
| Institution: | LIAO Zhi-qiong,GAN Ting,CHEN Xi-ming,WU Yai-hua,LIAO De-gui,CHEN Sheng-qiang,XIAO Guo-huan,FEAN Zhao-hui.The Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510260,China |
| Abstract: | Objective To investigate the relationship of IL-17 with preeclam psia.Methods Thirty patients with preeclampsia and thirty normal pregnant women as controls were investigated.Expression of IL-17 in placental specimens was detected by immunohistochemistry.Results Compared with the control group,expression of IL-17 was higher in preedampsia placentas(P<0.05).Conclusion IL-17 may contribute to the pathogenesis and pathophysiology of preeclampsia. |
| Keywords: | Interleukin-17 Preeclampsia Placenta |
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