| 以总多糖为指标考察肺热清解口服液的提取工艺 |
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| 引用本文： | 刘佩沂,;赖岳晓,;田素英.以总多糖为指标考察肺热清解口服液的提取工艺[J].广东药学,2014(9):658-660. |
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| 作者姓名： | 刘佩沂 ;赖岳晓 ;田素英 |
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| 作者单位： | [1]广东省中山市黄圃人民医院,广东中山528429; [2]广东药学院,广东广州510006 |
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| 基金项目： | 中山市卫生局科研项目（编号：2009078） |
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| 摘 要： | 目的优选肺热清解口服液的提取工艺。方法采用煎煮法,以料液比、提取次数和提取时间作为单因素水平,以总多糖含量为指标筛选水平;再通过L9（3^4）正交试验,以上述3个因素和单因素筛选的3个水平,以总多糖的含量、干膏得率为指标,对肺热清解口服液中总多糖的水提工艺进行系统研究。结果最佳提取工艺为A1B3C3,即药材加8倍水,煎煮3次,每次2 h。结论最佳提取工艺简便、稳定、可行。
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| 关 键 词： | 肺热清解口服液 总多糖 提取工艺 |
Optimization of Extract Parameters of Feireqingjie Oral Liquid with Total Polysaccharide Content |
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| Institution: | LIU Peiyi, LAI Yuexiao , TIAN Suying ( 1. Department of Pharmacy, Guangdong Zhongshan Huangpu People＇ s Hospital, Zhongshan, Guangdong, 528429, China;2. Guangdong Pharmaceutical University, Guangzhou, Guangdong, 510006, China) |
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| Abstract: | Objective To optimize the extraction process of Feireqingjie oral liquid. Methods Boiling with water was used to extract Feireqingjie oral liquid. The amount of water,extraction time and frequency were used as single factor level.The content of total polysaccharide was used as index to screen levels. The extraction technology of Feireqingjie oral liquid was optimized by L9（ 4^3） orthogonal experiment,with the 3 factors and the 3 chosen levels of every factor,and the total polysaccharide content and the yield as evaluation indexes. Results The optimum extraction condition was A1B3C3 which means Feireqingjie oral liquid was extracted 3 times by 8 folds of water,and extracted for 2 hour per time. Conclusion The best extraction process of is simple,stable and feasible. |
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| Keywords: | Feireqingjie oral liquid total polysaccharide contend extraction process |
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