急性冠脉综合征中医证候因素与冠状脉动脉病变程度关系研究

目的：以北京地区汉族患者的临床资料为依据，探讨急性冠脉综合征的中医证候因素与冠状动脉造影之间的关系，以期为中医微观辨证提供依据。方法：运用现代统计学方法，研究证候因素在病变支数上分布情况以及各证候因素的Gensini积分差异。结果：ACS中医证候因素分布与冠状动脉造影有关（P〈0．05）。8个证候因素在冠脉病变支数情况上的分布有统计学差异（P=0．007），不同证候因素的Gensini积分不同（P=0．001）。随着寒凝、血瘀的出现，冠脉病变范围和程度趋于严重。从本虚角度考虑，随着气虚、阴虚、阳虚病变程度逐渐加重。结论：ACS中医证候因素与冠状动脉造影病变支数分布和Gensini积分值有关。

Study of Relations between TCM Syndrome of Acute Coronary Syndrome and Severity of Coronary Artery Lesion

Objective：This study probed into the TCM syndrome pattern of acute coronary syndrome, in accordancewith the sufficient sampling from Beijing and the use of modern statistical methods. In order to present the basis in micro- cosmic determination of treatment based on differentiation of syndromes, we investigated the relationship between the changes in outcome of coronary angiography （CAG） and the types of TCM syndromes. Methods：Using the factor analysis method, this study explored the types of syndrome. We studied the relationship between the affection branches and the types of syrLdrome. And we also compared the difference between Gensini accumulated points. Results ：There were corre- lations between the types of TCM syndromes and coronary arteriongraphy. There was significant statistical difference in the number of aeteria coronaria pathologic changes over the distribution of the 8 types of TCM syndromes. The grades of Gensini were different in the different types of TCM syndromes. With the appearance of the accumulation - syndrome of pathogenic cold and the syndrome of blood stasis, the degree of pathological changes was increased. While considered the deficiency - syndrome of essence, the degree of aeteria coronaria pathologic changes was more and more serious with the appearance of the deficiency - syndrome of qi, the deficiency - syndrome of yin, the deficiency - syndrome of yang. Con- clusion：There were correlations between the types of TCM syndromes and coronary arteriongraphy.