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乳香的化学成分和药理活性研究进展
引用本文:常允平,韩英梅,张俊艳.乳香的化学成分和药理活性研究进展[J].现代药物与临床,2012,27(1):52-59.
作者姓名:常允平  韩英梅  张俊艳
作者单位:1. 天津药物研究院天津市新药设计与发现重点实验室,天津300193;天津中医药大学,天津300193
2. 天津药物研究院天津市新药设计与发现重点实验室,天津,300193
摘    要:乳香为橄榄科植物乳香树或同属植物的胶状树脂,主要含有五环三萜、四环三萜、大环二萜等萜类和多种挥发油类成分.研究表明药用乳香具有抗炎、抗肿瘤、抗哮喘、抗氧化等药理活性,有潜在的药用价值.综述了乳香化学成分和药理作用研究进展,为乳香的进一步研究提供参考.

关 键 词:乳香  乳香酸  乙酰基-11-羰基-β-乳香酸  抗肿瘤  抗炎

Research advance on chemical constituents and pharmacological action of Boswellia carterii
CHANG Yun-ping,HAN Ying-mei and ZHANG Jun-yan.Research advance on chemical constituents and pharmacological action of Boswellia carterii[J].Drugs & Clinic,2012,27(1):52-59.
Authors:CHANG Yun-ping  HAN Ying-mei and ZHANG Jun-yan
Institution:1,2 1.Tianjin Key Laboratory of Molecular Design and Drug Discovery,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 2.Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China
Abstract:Frankincense,the gum resin of Boswellia carterii or the other plants belonging to the same species,mainly consists of chemical constituents such as terpens(tetra-and penta-cyclic triterpens,diterpens) and essential oil.Investigations on the pharmacological effects of the resin have demonstrated its anti-inflammatory,antitumor,anti-asthma,anti-oxidative activities etc.,and these results indicate potential medicinal value of this material.In this review,the recent progresses in the research of chemical constituents and pharmacological activities are summarized,which will provide reference for further research of B.carterii.
Keywords:Boswellia carterii Birdw    boswellic acid  acetyl-11-keto-β-boswellic acid  antitumor  anti-inflammation
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