| 复方天葡片对大鼠＋10Gz暴露后血液流变学的影响 |
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| 引用本文： | 辛益妹,王永新,张清俊,詹皓,葛华.复方天葡片对大鼠＋10Gz暴露后血液流变学的影响[J].军医进修学院学报,2011,32(8):853-854,862. |
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| 作者姓名： | 辛益妹 王永新 张清俊 詹皓 葛华 |
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| 作者单位： | 空军航空医学研究所,北京,100142 |
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| 基金项目： | 国家科技重大专项(2010ZX9102-204); 国家自然科学基金(81072914); 全军医药卫生科研基金课题(06MA265); 军队中医药专项课题(10ZYZ255)~~ |
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| 摘 要： | 目的观察复方天葡片提取物对＋10Gz暴露后大鼠血液流变学指标的影响。方法 60只雄性SD大鼠随机分为5组：对照组,＋10Gz组,＂复方天葡片＂低剂量防护组、＂复方天葡片＂中剂量防护组、＂复方天葡片＂高剂量防护组,每组12只。暴露方案：＋10Gz,持续5min。于＋Gz应激后采集抗凝血,进行血流变学相关指标的检测。结果与对照组相比,＋10Gz组的高、中、低切全血黏度均显著升高;与＋10Gz组相比,给药组高、中、低切全血黏度明显下降。＋10Gz组红细胞压积与对照组相比显著升高（P〈0.01）,给予药物后红细胞压积回降明显,与＋10Gz组比有明显降低（P〈0.01）。低、中剂量组的全血高、中切还原黏度与＋10Gz组相比明显降低,与对照组接近。结论复方天葡片提取物对＋10Gz暴露后大鼠血液流变学改变有明显保护作用。
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| 关 键 词： | 复方天葡片 持续性正加速度 大鼠 血流变学 |
Effect of Fufang Tianpu tablet extraction on hemorheological changes in rats after +10Gz exposure |
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| XIN Yi-mei,WANG Yong-xin,ZHANG Qing-jun,ZHAN Hao,GE Hua.Effect of Fufang Tianpu tablet extraction on hemorheological changes in rats after +10Gz exposure[J].Academic Journal of Pla Postgraduate Medical School,2011,32(8):853-854,862. |
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| Authors: | XIN Yi-mei WANG Yong-xin ZHANG Qing-jun ZHAN Hao GE Hua |
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| Institution: | XIN Yi-mei,WANG Yong-xin,ZHANG Qing-jun,ZHAN Hao,GE Hua Institute of Aviation Medicine,Chinese PLA Air Force,Beijing 100142,China |
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| Abstract: | Objective To observe the effect of Fufang Tianpu tablet extraction on hemorheological changes in rats after +10Gz exposure.Methods Sixty male SD rats were randomly divided into control group,+10Gz group,and low,medium,high dose Fufang Tianpu tablet extraction groups.The rats were exposed to +10Gz for 5min.Anti-coagulated blood was collected from rats after +10Gz exposure and hemorheological parameters were detected.Results The low,medium and high shear blood viscosity was obviously higher in +10Gz group tha... |
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| Keywords: | FuFangTianPuPian Gz Stress Rats Hemorheology |
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