精神分裂症患者述情障碍与生活质量和精神症状的相关性研究

目的 探讨精神分裂症患者述情障碍与生活质量和精神症状的相关性,为药物治疗和心理干预提供依据.方法 将170例精神分裂症患者设为研究组,同期随机选取170名身心健康者设为对照组,对两组采用多伦多述情障碍量表和生活质量综合评定问卷-74进行测评分析,对研究组采用阳性与阴性症状量表评定精神症状.结果 研究组多伦多述情障碍量表总分及各因子分显著高于对照组(P＜0.01),生活质量综合评定问卷-74总分及各维度分显著低于对照组(P＜0.01);研究组多伦多述情障碍量表总分和因子III与生活质量综合评定问卷-74总分、心理功能、社会功能和物质生活状态维度呈显著负相关(P＜0.05或0.01),因子II与生活质量综合评定问卷-74总分、社会功能和物质生活状态维度呈显著负相关(P＜0.01);研究组多伦多述情障碍量表总分和因子II与阳性与阴性症状量表总分、阳性症状和阴性症状因子分呈显著正相关(P＜0.05或0.01),因子I与阳性与阴性症状量表总分和阳性症状因子分呈显著正相关(P＜0.01),因子III与阳性与阴性症状量表总分和阴性症状因子分呈显著正相关(P＜0.05或0.01).结论 精神分裂症患者的述情障碍与生活质量和精神症状存在一定的相关性,精神症状越严重,述情障碍越明显,生活质量越低.

Correlation study of alexithymia and quality of life or psychiatric symptoms in schizophrenics

Objective To explore the relationships between alexithymia and quality of life or psychiatric symptoms in schizophrenics in order to provide basis for medication and mental intervention. Methods 170 schizophrenics were assigned to research group 170 psychosomatic health persons selected randomly to con- trol group, assessments were carried out with the Toronto Alexithymia Scale （TAS） and Generic Quality of Life Inventory-74 （GQOLI-74） in both groups and mental symptoms with the Positive and Negative Symptom Scale （PANSS） in research group. Results The total and each factor score of the TAS were sig- nificantly higher （P〈0.01） and total and each dimension score of the GQOLI-74 lower （P〈0.01） in re- search than in control group; in research group the total and factorⅢ score of the TAS were significantly negatively related to the total, psychological function, social function and matter living condition of the GQOLI-74 （P〈0.05 or 0.01） and factor Ⅱ to the total score, social function and matter living condition （P〈0.05） ; in research group, the total and factor Ⅱscore of the TAS were significantly positively related to the total score, positive and negative symptoms scores of the PANSS （P〈0.05 or 0.01）, factor Ⅰ to the total score and positive symptoms score （P〈0.05） and factor Ⅲ to the total score and negative symptoms scores （P〈0.05 or 0.01）. Conclusion Alexithymia has some correlation with quality of life and mental symptoms, the severer mental symptoms are, the more obvious alexithymia becomes and the lower quality of life is.