| 银杏叶聚戊烯醇抗癌作用的初步研究 |
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| 引用本文： | 高凌,亢寿海,张琴芬,张能芳,钱新华,徐荣华.银杏叶聚戊烯醇抗癌作用的初步研究[J].药学与临床研究,2003,11(1):1-3. |
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| 作者姓名： | 高凌 亢寿海 张琴芬 张能芳 钱新华 徐荣华 |
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| 作者单位： | 江苏省肿瘤防治研究所,南京,210009 |
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| 基金项目： | 江苏省科技厅社会发展项目资助 (BS2 0 0 10 6 5) |
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| 摘 要： | 目的 :研究银杏叶 (FoliumGinkgo)提取物—聚戊烯醇 (PolyprenolsGP 1 )的抗肿瘤作用。方法 :采用动物抗移植性肿瘤实验方法。结果 :1 0 0mg/kg的聚戊烯醇对移植性肝癌Heps和肉瘤S1 80 的实验抑制率分别为 49 1 3 %和 46 53% ,40 0mg/kg的聚戊烯醇对艾氏癌EC抑制率为 49 65 % (P <0 0 1 )。银杏叶聚戊烯醇对艾氏腹水癌EAC小鼠无明显延长寿命作用。结论 :银杏叶聚戊烯醇有良好的抗肿瘤作用 ,应进行深入研究
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| 关 键 词： | 聚戊烯醇 抗肿瘤 Heps S180 EAC |
| 文章编号： | 1007-306(2003)01-01-03 |
| 修稿时间： | 2002年6月5日 |
A Preliminary Study of Antitumor Effects of Polyprenols Extracted from Folium Gingko |
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| Gao Ling,Kang Shouhai,Zhang Qinfen,Zhang Nengfang,Qian Xinhua,Xu Ronghua Jiangsu Institute of Cancer Research\.A Preliminary Study of Antitumor Effects of Polyprenols Extracted from Folium Gingko[J].Pharmacertical and Clinical Research,2003,11(1):1-3. |
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| Authors: | Gao Ling Kang Shouhai Zhang Qinfen Zhang Nengfang Qian Xinhua Xu Ronghua Jiangsu Institute of Cancer Research\ |
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| Institution: | Nanjing\ 210009 |
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| Abstract: | Objective:to study the effects of Polyprenols (GP 1),an extract of Folium Gingko , on tumor Methods:Using grafting tumor models in mice to detect the inhibitory rates Results:The inhibitory rates were 49 13% and 46 53% on Heps and S 180 respectively when GP 1 was given orally at the dose of 10 0mg/kg;And the inhibitory rate was 49 65% on EAC at the dose of 40 0mg/kg,but GP 1 had no effect of prolonging lifespan Conclusion:GP 1 had significant antitumour effects,it's worthy to do some additional research |
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| Keywords: | Polyprenols Antitumour HEPS S 180 EAC |
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