| 急性缺氧对大鼠脑内亮-脑啡肽样免疫活性物质含量的影响 |
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| 引用本文： | 邢温玉,崔瑞耀,崔向东,徐珞.急性缺氧对大鼠脑内亮-脑啡肽样免疫活性物质含量的影响[J].青岛大学医学院学报,1986(3). |
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| 作者姓名： | 邢温玉 崔瑞耀 崔向东 徐珞 |
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| 作者单位： | 青岛医学院生理学教研室
(邢温玉，崔瑞耀，崔向东)，青岛医学院生理学教研室(徐珞) |
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| 摘 要： | 本工作选用健康雄性大鼠、常压低氧含氮空气,以放射免疫测定法,初步探讨了大鼠经急性中度缺氧刺激后,其垂体及各脑区亮-脑啡肽样免疫活性物质(LEKIS)含量的变化.结果表明:垂体及各脑中LEKIS含量均有不同程度下降,其中垂体、下丘脑、中脑、丘脑及海马与对照组相比,下降非常显著(P<0.01);皮层(额叶)下降显著(0.05>P>0.01);纹状体及桥延部也有所下降,但统计学无显著差别(P>0.05).
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| 关 键 词： | 缺氧 亮-脑啡肽 放射免疫测定 大鼠 |
THE EFFECT ACUTE HYPOXIA ON CONTENTS OF LEUCINE-ENKEPHALIN IN PIYUITARY AND BRAIN OF RATS |
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| Xing Wenyu,et al.THE EFFECT ACUTE HYPOXIA ON CONTENTS OF LEUCINE-ENKEPHALIN IN PIYUITARY AND BRAIN OF RATS[J].Acta Academiae Medicinae Qingdao Universitatis,1986(3). |
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| Authors: | Xing Wenyu |
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| Institution: | Xing Wenyu,et al Department of Physiology,Qingdao Medical College |
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| Abstract: | By means of radioimmunoassay, we measured the contents of Lencineenkephalin-like immunoactive-substances in the pituitary and seven areas of the male rats brain in the condition of acute hypoxia(mixtured of air and nitrogen ). The results obtained were as follws: The contents are greatly decreased in the pituitary, hypothalamus, mesencephalon, thalmus and hippocampus compared with the control groups (P<0.01); They ar also remarkly decreased in the cerebral cortex(P<0.05).The contents are decreased in pons-medullaoblongata and striatum, but these changes. are not remarkable difference in statistics(P>0.05). |
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| Keywords: | Hypoxia Leu-enkephalin Rodioimmunoassay Rats |
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