Correlative Expression of Glutathion S-Transferase-π and Multidrug Resistance Associated Protein in Bladder Transitional Cell Carcinoma |
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引用本文: | 杨为民,曾晓勇,陈春莲,陈忠,杜广辉.Correlative Expression of Glutathion S-Transferase-π and Multidrug Resistance Associated Protein in Bladder Transitional Cell Carcinoma[J].华中科技大学学报(医学英德文版),2000,20(4). |
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作者姓名: | 杨为民 曾晓勇 陈春莲 陈忠 杜广辉 |
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作者单位: | Department of Urology,Department of Pathology,Tongji Hospital,Tongji Medeical University,Wuhan 430030 |
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基金项目: | This project was supported by a grant from the fund of science of Hubei Province (No. 99J124 ). |
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摘 要: | Chemotherapylswidelyappliedlnthetreatmentofsuperficial(instravesicaIinstiIlation)andinvasive(systemicadministration)bladdercancer.However,resistancetochemotherapenticagentsstillremainsacriticalprobIemintherapy,whichkeepsamuchhigherrecurrentrateofbIaddercancerandpreventsthecureofpat1ents.Previous1y,theresearchesonthemechanismsofdrugsres1stanceusuallyconcen-trateonthemembersoftheATP--bindingcassette(ABC)transportersuperfamlly(forinstance,P--gp,MRP,LRP,etc.)'2],butatpresentincreasingevi-d…
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关 键 词: | bladder neoplasm carcinoma glutathion S-Transferase-π multidrug resistance as- sociated protein |
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