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Correlative Expression of Glutathion S-Transferase-π and Multidrug Resistance Associated Protein in Bladder Transitional Cell Carcinoma
引用本文:杨为民,曾晓勇,陈春莲,陈忠,杜广辉.Correlative Expression of Glutathion S-Transferase-π and Multidrug Resistance Associated Protein in Bladder Transitional Cell Carcinoma[J].华中科技大学学报(医学英德文版),2000,20(4).
作者姓名:杨为民  曾晓勇  陈春莲  陈忠  杜广辉
作者单位:Department of Urology,Department of Pathology,Tongji Hospital,Tongji Medeical University,Wuhan 430030
基金项目:This project was supported by a grant from the fund of science of Hubei Province (No. 99J124 ).
摘    要:Chemotherapylswidelyappliedlnthetreatmentofsuperficial(instravesicaIinstiIlation)andinvasive(systemicadministration)bladdercancer.However,resistancetochemotherapenticagentsstillremainsacriticalprobIemintherapy,whichkeepsamuchhigherrecurrentrateofbIaddercancerandpreventsthecureofpat1ents.Previous1y,theresearchesonthemechanismsofdrugsres1stanceusuallyconcen-trateonthemembersoftheATP--bindingcassette(ABC)transportersuperfamlly(forinstance,P--gp,MRP,LRP,etc.)'2],butatpresentincreasingevi-d…

关 键 词:bladder  neoplasm  carcinoma  glutathion  S-Transferase-π  multidrug  resistance  as-  sociated  protein
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