| 2型糖尿病患者胆结石发生的高危因素分析 |
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| 引用本文： | 蒋晓红.2型糖尿病患者胆结石发生的高危因素分析[J].江苏大学学报(医学版),2002,12(2):149-150. |
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| 作者姓名： | 蒋晓红 |
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| 作者单位： | 常州市第一人民医院内分泌科,江苏,常州,213003 |
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| 摘 要： | 目的：探讨2型糖尿病患者胆结石与高胰岛素、脂代谢紊乱的关系。方法：采用病例对照研究的方法，观察50例伴胆结石与60例不伴胆结石的2型糖尿病患者血清胰岛素、胰岛素敏感指数、C肽、血脂的变化。结果：发现伴胆结石患者的血清胰岛素、C肽、甘油三酯、胆固醇显著高于不伴胆结石组（P＜0．05），高密度脂蛋白、胰岛素敏感指数显著低于不伴胆结石组（P＜0．05），载脂蛋白－A1明显降低（P＜0．01），而两组低密度脂蛋白、脂蛋白－a、载脂蛋白－B1无差异。结论：高胰岛素血症、脂代谢异常可能中老年2型糖尿病患者胆结石 形成的高危因素。
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| 关 键 词： | 糖尿病 胰岛素 胆结石 血脂 |
| 文章编号： | 1006-7655(2002)02-0149-02 |
| 修稿时间： | 2002年3月25日 |
The Analysis of High Risk Factor in Cholelithiasis Subjects with Type 2 Diabets |
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| JIANG Xiao-hong.The Analysis of High Risk Factor in Cholelithiasis Subjects with Type 2 Diabets[J].Journal of Jiangsu University Medicine Edition,2002,12(2):149-150. |
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| Authors: | JIANG Xiao-hong |
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| Abstract: | Objective:To study the correlation between cholelithiasis and hyperinsulinemia or dyslipoidosis in type 2 diabetes.Methods: A case-matched study was carried out to investigate the changes of insulin,insulin sensitivity index(ISI)cp, serum lipids in type 2 diabetic patients with cholelithiasis and without cholelithiasis. Result:fifty diabetics with cholelithiasis had higher triglyceride(TG), insulin, cp, and cholesterol(CH) ( P <0.05),lower hight density lipoprotein cholesterol(HDL-C),ISI ( P <0.05),Apo-A1( P <0.01) than sixty diabetics without cholelithasis.There are no significant differences in lowdensity lipoprotein cholesterol(LDL-C),Lpo-a,Apo-B1.Conclusions:The results indicate that highinsulinemia,dyslipoidosis might be a risk factor for the development of cholelithiasis in type 2 diabetic patients. |
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| Keywords: | Diabetes Insulin Cholelithiasis Lipids |
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