感染性眼内炎病因与疗效相关因素分析

目的探讨感染性眼内炎（IE）病因与疗效影响因素。方法调研某医院2008-2020年130例IE病人资料，分析不同病因病人临床特征及影响疗效的相关因素。结果外源性眼内炎（ExE）100例，内源性眼内炎（EnE）30例。男、女病人均以ExE为主。未成年和青壮年人以ExE为主，老年人以EnE为主。90.00%的EnE病人并发全身基础疾病，主要为糖尿病、肝脓肿和高血压。病原菌检出率18.46%，EnE为36.67%，高于ExE的13.00%（P < 0.01）。病原菌主要为肺炎克雷伯菌、葡萄球菌等。治愈、好转率分别为63.1%、36.9%，年龄≤60岁、外源性、无合并全身基础病和无合并肝脓肿者IE的治愈率高于年龄>60岁、内源性、合并全身基础病和合并肝脓肿者IE的治愈率（P < 0.05~P < 0.01）。结论IE治愈率较低，病因复杂，治疗应结合影响疗效的因素，注重针对性。

Analysis of the etiology and efficacy of infectious endophthalmitis

ObjectiveTo investigate the etiology and efficacy of infectious endophthalmitis (IE).MethodsThe data of 130 patients with IE in a hospital from 2008 to 2020 were investigated, and the clinical characteristics of patients with different etiologies and related factors affecting the curative effect were analyzed.ResultsA total of 100 cases of exogenous endophthalmitis (ExE) and 30 cases of endogenous endophthalmitis (EnE) were enrolled.ExE was predominant in both male and female patients.ExE was mainly found in nonages and young adults, and EnE was mainly found in the elderly.Ninety percent of EnE patients were complicated with systemic diseases, mainly including diabetes mellitus, liver abscess and hypertension.The detection rate of pathogenic bacteria was 18.46%, 36.67% in EnE, which was higher than 13.00% in ExE (P < 0.01).The main pathogens were Klebsiella pneumoniae and Staphylococcus, etc.The cure and improvement rates were 63.1% and 36.9%, respectively.The cure rate of IE in patients aged ≤ 60 years, exogenous, without systemic disease, and without liver abscess was higher than that in patients aged >60 years, endogenous, with systemic disease, and with liver abscess (P < 0.05 to P < 0.01).ConclusionsThe cure rate of IE is low, and the etiology is complicated.The treatment should be combined with the factors affecting the curative effect and pay attention to the pertinence.