2018年某院辅助用药重点监控品种使用情况分析

目的对西安医学院附属宝鸡医院排名前10位的辅助用药重点监控品种的使用情况进行分析,为加强辅助用药的监管和促进临床合理用药提供参考。方法通过医院信息系统将2018年重点监控药品的科室分布、销售金额、用药频度(DDDs)、日均费用(DDC)和药品排序比(B/A)进行统计分析,并对其使用合理性进行医嘱点评分析。结果重点监控品种使用科室大多与其科室疾病谱相符。销售金额排序前3位依次为小牛血清去蛋白注射液、丹参川芎嗪注射液和醒脑静注射液;按DDDs排序前3位依次为丹参川芎嗪注射液、小牛血清去蛋白注射液、腺苷钴胺注射液;按DDC排序前3位依次为醒脑静注射液、小牛血清去蛋白注射液、转化糖电解质注射液;鹿瓜多肽注射液、注射用硫辛酸、舒血宁注射液和注射用血栓通的B/A接近1。不合理应用集中表现在适应症不适宜、给药剂量不规范,构成比分别为59.41%、16.01%。结论西安医学院附属宝鸡医院重点监控药品管理工作初见成效,但仍需采取积极有效的监管措施进一步促进重点监控药品的合理使用。

Analysis on utilizazation of key monitoring varieties among adjuvant drugs in a hospital in 2018

Objective To investigate the utilization of key monitoring varieties among the top 10 adjuvant drugs in Affiliated Baoji Hospital of Xi'' an Medical University, and provide references for reinforcing the supervision and management for adjuvant drugs and promoting rational clinical use of drugs. Methods The drug information management system was used to collect the department distribution, sales amount, frequency of drug use (DDDs), defined daily cost (DDC), and the drug sequence ratio (B/A) of key monitoring drugs in 2018. And the rationality of their use was analyzed. Results The department distribution of key monitoring varieties were in line with their disease spectrum. Sales amounts of Deproteinised Calf Blood Serum Injection, Danshen Chuanxiongqin Injection, and Xingnaojing Injection were ranked the top three. DDDs of Chuanxiongqin Injection, Deproteinised Calf Blood Serum Injection, and Adenosine Cobalamin Injection were ranked the top three. DDC of Xingnaojing Injection, Deproteinised Calf Blood Serum Injection, and Invert Sugar and Electrolytes Injection were ranked the top three. B/A of Cervus and Cucumis Polypeptide Injection, Thioctic Acid for injection, Shuxuening Injection, and Xueshuantong for injection were close to 1. After the intervention, the sales amount and amount of usage of those key monitoring varieties among adjuvant drugs decreased. The clinical irrational utilization of adjuvant drugs mainly manifested as inappropriate indications and nonstandard dosing, accounting for 59.41% and 16.01%. Conclusion The supervising of key monitoring medicines has achieved certain results in Affiliated Baoji Hospital of Xi''an Medical University, and positive and effective measures are needed to supervise the irrational use of drugs and promote the rational drugs use.