2004-2006年吉林省流行性感冒病原学变化特点

目的探讨吉林省流行性感冒的病原学变化特点。方法根据2004—2006年流感监测结果对吉林省流感的流行趋势、病原学变化特点进行综合分析。用细胞培养法分离并鉴定流感病毒，用微量半加敏血凝抑制试验方法检测人群中抗流感病毒抗体水平。结果监测哨点医院2004—2006年临床诊断的流感样病例数基本持平，冬季可见1个波峰；全省发生暴发疫情0起；两个监测年从1350标本中分离病毒71株，其中甲1型39株（54．93％），甲3型7株（9．86％），乙型（yamagata株系）流感病毒24株（33．80％），乙型（victorian株系）流感病毒1株（1．41％），正常人群抗体水平测定以抗A3抗体最高，抗乙型（victorian株系）抗体最低。结论2004—2006年吉林省流感流行以低水平散发为主。提示在今后的监测工作中除了及时发现甲型变异株的出现，还应密切关注乙型（victorian株系）的流行动态。

Virological Characteristic of Influenza in Jilin Province

Objective To study influenza epidemic tendency in Jilin.Methods The influenza epidemic tendency and the etiological characteristic were analyzed by the result of surveillance in 2004-2006.MDCK was to isolate the influenza viruses from samples,and human antibodies against influenza viruses were detected by using the Heamlogical inhibitor.Results ILI was like in tow years,there were one peak in winter,71 isolates of influenza virus were isolated from 1 350 clinic samples,A1 type were 39(54.93%),A3 virus were 7(9.86%),B type(Yamagata-like) virus were 24(33.80%),B type(victorian-like) virus were 1(1.41%).The antibody of influenza A3 was MAX,The antibody of type B(victorian-like)was MIN.Conclusion Influenza in vogue is by lower level to spread in Jilin province 2004-2006.Besides finding out the variation substance of first-model in time,We should pay attention to prevalent developments of second-model(victorian-like).