未足月胎膜早破129例临床分析

目的探讨未足月胎膜早破(preterm premature rupture of membrane,PPROM)发生的易发因素及妊娠结局,选择终止妊娠的方式与时机。方法回顾性分析2005年1月至2006年12月在我院产科住院的PPROM病例129例。结果69.77%的PPROM有感染因素存在,比较孕28~34+6周与孕35~36+6周的PPROM,发现其分娩方式差异无显著性(p>0.05),前组剖宫产率明显低于后组(p<0.05)。孕28~34+6周的PPROM新生儿窒息,呼吸窘迫综合征(respir-atory distress syndrome,RDS)发生率和死亡率明显高于35~36+6周者。结果早产合并胎膜早破在严密监护下适当延长孕龄,可减少新生儿窒息及降低围产儿的病死率,并不增加剖宫产率。

Clinical analysis of 129 cases of preterm premature rupture of membrane

Objective To study the risk factors of preterm premature rupture of membrane (PPROM)and pregnant outcome,to choose the method and chance to terminate pregnancy.Methods From january 2005 to december 2006,retrospective study was done on 129 cases of PPROM.Results 69.77percent of cases had high risk factors of PPROM.A comparison of 28~34+6weeks with 35+36+6weeks shows the labour styles were insignificant(p>0.05).28-34+6weeks had higher neonatal asphyxia and neonate respiratory distress syndrome (RDS)rates than 35-36+6weeks,In addition,more mortality and lower rate of caesarean section (p<0.05)in 28-34+6weeks.Conclusion Under close surveillance,the gestational age of PPROM can be prolonged properly to decrease the rate of neonatal asphyxia and the fatality rate of perinatal.There is no increasing in the rate of cesarean section.