愈疡膏外敷联合西药治疗复发型活动期溃疡性结肠炎临床研究

目的:探讨愈疡膏贴敷神阙穴联合西药治疗溃疡性结肠炎的疗效及其可能的作用机制。方法:将80例溃疡性结肠炎患者按随机数字表法分为中西药联合治疗组和西药对照组各40例。治疗组采用愈疡膏贴敷神阙穴加美沙拉嗪片及复方嗜酸乳杆菌片治疗,对照组采用安慰膏贴敷神阙穴加美沙拉嗪片及复方嗜酸乳杆菌片治疗,疗程为90 d。评价其对溃疡性结肠炎患者的综合疗效,生活质量的影响,并探讨其可能的作用机制。结果:治疗组总有效率为86.8%,对照组为64.9%,治疗组优于对照组(P<0.05);治疗组可降低血小板计数、血清钙卫蛋白、IL-17F。治疗组IBDQ量表全身症状、肠道症状、情感能力和社会能力评分及总分均高于西药组(P<0.05)。结论:愈疡膏贴敷神阙穴配合西药治疗溃疡性结肠炎能控制溃疡性结肠炎活动,促进溃疡愈合,提高患者生活质量。     

The Influence of Engravings on the Sticking of Tablets. Investigations with an Instrumented Upper Punch

The purpose of this study was to investigate the influence of engravings on the sticking of tablets. Therefore, an instrumented upper punch capable of measuring the pull-off force, which occurs when the punch detaches itself from the upper surface of a tablet, was equipped with small cones of different angles between the punch face and the cones’ lateral face. The cones could be screwed into a threaded hole at the center of the punch face. The adhesion forces of two formulations known to stick to engravings during production increased with a greater steepness of the cones’ lateral face. With microencapsulated acetylsalicylic acid, no quantitative differences could be found between the adhesion forces obtained with plain and modified punch faces, indicating that the sticking behavior of the substance was not affected by shear forces. Starch 1500® showed higher adhesion force signals in comparison to those obtained with a plain punch face. Microcrystalline cellulose, which gave no adhesion force signals with a plain punch face and did not stick to the cones, showed distinct pull-off signals. The instrumented upper punch equipped with shear cones is a valuable instrument for detecting the adhesion caused by engravings and is therefore a helpful tool for tablet formulation development and the design optimization of tablet identification.     

针刺加耳穴贴压治疗紧张性头痛的临床研究

目的:观察针刺加耳穴贴压治疗紧张性头痛(TTH)的临床疗效.方法:将90例TTH患者采用随机数字表法分为针刺组、耳穴贴压组和观察组,每组30例.观察组接受针刺及耳穴贴压治疗,针刺组仅接受针刺治疗,耳穴贴压组仅接受耳穴贴压治疗.观察治疗前、治疗后及治疗后3个月随访时的头痛发作频率,以及头痛程度视觉模拟量表(VAS)、焦虑自评量表(SAS)和抑郁自评量表(SDS)评分.治疗后3个月随访时进行疗效评价.结果:随访时,3组疗效差异有统计学意义(P<0.01或P<0.05),疗效等级从高到低排列依次为观察组、针刺组和耳穴贴压组.治疗后和随访时,3组的头痛程度VAS评分、头痛发作频率、SAS和SDS评分均显著低于本组治疗前(均P<0.01);观察组上述4项结果均低于同时间点针刺组和耳穴贴压组(均P<0.01);针刺组VAS评分低于耳穴贴压组(均P<0.05).随访时针刺组头痛频率低于耳穴贴压组(P<0.05).结论:针刺加耳穴贴压以及针刺和耳穴贴压单独应用均能减轻TTH患者的头痛程度,减少头痛发作次数,改善焦虑及抑郁情绪,且针刺加耳穴贴压的效果最显著.     

颞肌贴敷术治疗烟雾病的围术期护理

目的探讨颞肌贴敷术治疗烟雾病的围术期护理要点。方法对12例行颞肌贴敷术治疗的烟雾病患者术前予抗血管痉挛,改善微循环,做好术前的一般护理,术后注意加强瞳孔意识生命体征的监测,做好引流管,体位,饮食的护理。结果患者术后均康复出院。结论积极有效的术前和术后护理,有助于提高手术疗效,对促进患者康复至关重要。     

Clinical observation on acupuncture plus auricular point sticking in treating insomnia

Insomnia is a common sleep disorder and usually affects the patients' emotions and work.We applied acupuncture plus auricular point sticking to treat insomnia and reported it as follows.     

Effects of point application on celiac mast cell degranulation in mice with allergic rhinitis: An experimental study

目的：研究不同处理方法对卵白蛋白（Ovum Albumin，OVA）变应性鼻炎小鼠模型腹腔肥大细胞脱颗粒的影响。方法：将60只雌性小鼠随机分为5组，每组12只，分别按不同方法处理后分离各组小鼠的腹腔肥大细胞，中性红染色后计算腹腔肥大细胞脱颗粒率。结果：正常对照组、OVA变应性鼻炎组、穴位敷贴组、激素对照组、磷酸盐缓冲液（Phosphate Buffer Saline，PBS）阴性对照组小鼠腹腔肥大细胞脱颗粒率分别为（15±6）％、（53±11）％、（37±13）％、（31±15）％、（47±14）％。OVA变应性鼻炎小鼠的腹腔肥大细胞有明显的脱颗粒现象：与OVA变应性鼻炎小鼠相比，穴位敷贴组及激素对照组小鼠的腹腔肥大细胞脱颗粒现象显著减轻；PBS对照组小鼠的腹腔肥大细胞脱颗粒现象没有明显变化。结论：推测穴位敷贴抗过敏机制为稳定肥大细胞膜，抑制肥大细胞脱颗粒，减少致炎介质产生。     

Clinical Observation on Application of Jiao Tai Pill on Shenque （CV 8） in Treating Insomnia

目的：观察神阙穴贴敷交泰丸治疗失眠症的临床疗效。方法：将152例失眠患者按就诊顺序随机分为2组，治疗组76例，采用交泰丸贴敷神阙穴治疗；对照组76例，采用口服交泰丸治疗，疗程均为4星期。于治疗前和治疗第1、2、4星期末及停药后第1、2、4星期末采用匹兹堡睡眠质量指数量表评定临床疗效。结果：治疗4星期，两组患者的睡眠质量均得以改善，组间差异无统计学意义，且无不良反应，停药后睡眠改善持续时间长。结论：交泰丸神阙穴贴敷与口服治疗失眠症疗效肯定，停药后反跳现象不明显。     

穴位贴敷治疗支气管哮喘述要

[目的]从支气管哮喘中西医浅见认识及穴位贴敷治疗的认识,讨论穴位贴敷疗法对支气管哮喘的疗效。[方法]运用三伏天中药穴位贴敷疗法。取穴:肺俞、心俞、膈俞(均为双侧),观察门诊支气管哮喘患者30例。[结果]30例中痊愈12例,占40%;有效14例,占46.67%;无效4例,占13.33%,总有效率为86.67%。[结论]穴位贴敷疗法对支气管哮喘具有显著疗效。值得临床推广应用。     

Observations on the Curative Effect of Auricular Point Sticking Therapy on Vertebral Artery Type of Cervical Spondylosis

目的：评价耳穴贴压法治疗椎动脉型颈椎病的疗效。方法：采用同期随机单盲对照方法。治疗组42例采用耳穴贴压法，对照组38例采用中成药治疗。15d为1个疗程，最多不超过2个疗程治疗。结果与结论：治疗组总有效率为97．6％，对照组总有效率为73．7％。两组比较差异有统计学意义，治疗组明显优于对照组。     

针灸天枢穴联合中药贴敷治疗老年性便秘疗效观察

目的观察针灸天枢穴联合中药贴敷治疗老年性便秘的疗效。方法将59例住院的老年性便秘患者分为两组．治疗组31例,在针灸天枢穴位的基础上给予穴位中药贴敷。对照组28例,单纯采用针灸双侧天枢穴。观察比较两组2周后的治疗效果。结果观察组总有效率为96．8％,对照组总有效率为78．6％,两组疗效比较差异有统计学意义（P〈0．05）。结论针灸天枢穴联合中药贴敷治疗老年性便秘有显著疗效。