Effect of different desensitizers on inhibition of bovine dentin demineralization: micro‐computed tomography assessment

This study evaluated the effect of two desensitizers on inhibition of dentin demineralization, after immersion in artificial saliva using micro‐computed tomography (μCT). Dentin blocks cut from bovine incisors were treated with deionized water (DW, a negative control) or one of three desensitizers: a fluoride varnish (Duraphat, a positive control), a calcium phosphate desensitizer (Teethmate Desensitizer), and a fluoro‐alumino‐calcium silicate‐based desensitizer (Nanoseal). After each treatment, the specimens in Duraphat, Nanoseal, and Teethmate Desensitizer groups were pre‐immersed in artificial saliva (pH 6.5) for either 1 d or 1 wk. The mineral loss of the specimens after demineralization (pH 5.0, 3 h) was evaluated by μCT. The treated surface was investigated with scanning electron microscopy. Mineral loss in all treatment groups was significantly lower than that in DW. Duraphat was the most effective treatment against demineralization, followed by Nanoseal. Nanoseal showed significantly better reduction in mineral loss following immersion for 1 wk in artificial saliva than for 1 d. However, Teethmate Desensitizer and Duraphat did not exhibit enhanced inhibition of demineralization over a longer period of immersion in artificial saliva. Scanning electron microscopy images showed deposition of particles on the dentin in both Teethmate Desensitizer. The application of Teethmate Desensitizer and Nanoseal to the exposed dentin surface resulted in inhibition of demineralization, with Nanoseal resulting in improved inhibition after prolonged immersion in artificial saliva.     

脉冲Nd:YAG激光辅助极固宁脱敏剂治疗老年牙本质过敏症的临床研究

目的：研究脉冲Nd：YAG激光辅助极固宁脱敏剂治疗老年牙本质过敏症的临床效果。方法：实验组用脉冲Nd：YAG激光1W（30mJ／cm^2、15Hz）照射120sec后，涂擦极固宁脱敏剂3次;对照组强采用极固宁脱敏剂3次。结果：实验组即刻、3个月及6个月有效率分别为87．29％、81．36％和75．42％，对照组的有效率为79．09％、63．64％和52．73％。即刻两组差异无屁著性（P〉0．05），而3个月、6个月差异有显著性（P〈0．01）。结论：脉冲Nd：YAG激光辅助极固宁脱敏荆治疗老年牙本质过敏症是一种高效、作用持久、使用安全的方法。     

Gluma脱敏剂治疗基牙预备后牙本质过敏的疗效观察

目的：评价Gluma脱敏剂对基牙预备后牙本质过敏的治疗效果。方法：将40例132个患牙随机分为两组，分别采用氟化钠甘油和Gluma脱敏剂治疗并进行疗效对比。结果：Gluma脱敏剂疗效明显优于氟化钠甘油。结论：Gluma脱敏剂对可摘局部义齿基牙预备后牙本质过敏有较好的治疗效果。     

Gluma脱敏剂治疗活髓牙全冠牙体预备后敏感症的临床疗效和扫描电镜观察

目的:探讨Gluma脱敏剂治疗金属烤瓷全冠牙体预备后敏感症的疗效及作用机理。方法:自身配对设计将15例62颗患牙随机分为Gluma治疗组和空白对照组,可视分级评价法(visualanalogscale,VAS)评价其临床疗效;制作离体牙标本,扫描电镜观察Gluma脱敏剂对牙本质小管的封闭作用。结果:Gluma脱敏剂治疗后VAS值(3.43±1.49)与治疗前(6.20±1.20)、对照组治疗后(5.87±1.47)均有显著差异(P<0.05),有效率83.87%;牙本质小管被封闭,表面均匀平整。结论:Gluma脱敏剂能缓解活髓牙全冠备牙后的敏感症状。     

������������������С�ܷ�����ü�����ĥ���о�

??Abstract??Objective To evaluate the the sealing effects and abrasive resistance of ClinproTM XT Varnish and Oravive through scanning electron microscope ??SEM??. Methods Totally 48 freshly extracted human premolars were selected?? prepared into dentin discs?? and randomly divided into 3 groups ??group A?? control group?? group B?? ClinproTM XT Varnish group??group C?? Oravive group??. ClinproTM XT Varnish and Oravive were applied respectively on the exposed dentin surfaces of the B and C group in accordance with operating manual. Eight teeth of the B and C group were respectively selected for toothbrush abrasion test. Then an observation was made on the surface and the section plane by scanning election microscope and quantitative analysis was made with Image-Pro Plus 6.0. Results Both of the two desensitizers could occlude the dentinal surface?? and dentinal tubule area and the relative area of the two groups had no significant difference ??P > 0.05??. The two desensitizers could penetrate into the dentinal tubules at a certain depth?? but the penetration depth in group B was larger than that in group C ??P < 0.05???? after the toothbrush abrasion test?? the sealing effect in group B was markedly superior to that in group C ??P < 0.05??. Conclusion ClinproTM XT Varnish performs better than Oravive in sealing effect and abrasion resistance.     

不同脱敏剂对牙列缺损行固定桥修复牙体预备后牙本质过敏影响的对比

目的：探讨不同脱敏剂对牙列缺损行固定桥修复牙体预备后牙本质过敏的影响。方法选取因牙列缺损就诊且行固定桥修复的患者90例,根据在固定修复牙体预备后采用的不同脱敏剂将患者分为保护膜和 Gluma 脱敏剂组,每组45例患者。比较两组患者治疗后疼痛感、临床疗效和患者满意度。结果治疗后两组的疼痛感均显著降低,而保护膜组患者疼痛感明显的低于 Gluma 脱敏剂组患者;保护膜组疗效显著的患者数以及总有效率均明显的高于 Gluma脱敏剂组患者,且差异具有统计学意义;两组患者的满意度的分布以及总满意度的差异均无统计学差异。结论牙本质保护膜措施应用于牙列缺损行固定桥修复牙体预备后患者改善疼痛和敏感的疗效明显的优于 Gluma 脱敏剂涂抹措施,值得临床推广。     

不同脱敏剂对楔状缺损充填后微渗漏的影响

目的:比较不同脱敏剂对楔状缺损充填后的微渗漏的影响。方法:选取30颗前磨牙随机分成3组并制作楔状缺损洞型,分别用MEdental,Gluma脱敏剂对牙本质进行表面处理,流动树脂充填,对照组牙本质表面不做任何处理,经牙合力循环、热循环后,用2%亚甲基蓝染色,24h后将每个离体牙由颊舌向沿牙长轴连续切下3片。在体视显微镜下放大40倍观察充填体边缘染液微渗漏情况,然后在SEM下观察流动树脂与牙体组织之间的粘结情况。结果:3组间充填体微渗率差异均有统计学意义(P0.05),以MEdental材料的边缘微渗率最低(P0.01);扫描电镜下观察可见:Medental组树脂与牙体组织结合良好,Gluma组树脂与牙体组织结合处部分位置出现裂隙,对照组树脂与牙体组织结合处存在裂隙且较Gluma组明显。结论:MEdental脱敏剂和Gluma脱敏剂均能降低楔状缺损充填后的微渗率,MEdental脱敏剂影响较大,使用Gluma脱敏剂和MEdental脱敏剂可以获得较好的边缘封闭性。     

复合树脂联合脱敏剂对楔状缺损牙敏感性及修复疗效的影响

目的：评价复合树脂充填楔状缺损时,联合应用脱敏剂对术后敏感和远期临床疗效的影响。方法：将167例542颗因楔状缺损导致牙本质敏感的患者按简单随机化分组方法,分为三组：涂布iBond七代自酸蚀粘接剂后复合树脂充填（A组）、涂布自酸蚀粘接剂可乐丽菲露后复合树脂充填（B组）及涂布舒齿灵脱敏剂后涂布可乐丽粘接剂七代自酸蚀粘接剂后复合树脂充填（C组）,比较术后脱敏疗效,并于充填后6、12及24个月用改良USPHS系统评价其远期临床疗效。结果：楔状缺损修补术后,各组牙牙本质敏感症状均有明显的缓解（尸〈0．05）;无牙本质敏感症状的牙所占比例A、C组显著性高于B组（P〈0．05）;三组在6、12个月时充填体成功率无显著差异,但C组24个月修复体成功率显著性低于A,B组。结论：对因牙本质敏感求治的楔状缺损患者,推荐术前使用脱敏剂或使用含有脱敏成分的粘接剂;使用iBond粘接剂进行复合树脂充填,能显著减少牙敏感症状,并且具有良好的粘接性能。     

三种脱敏剂对全酸蚀粘结剂牙本质粘结强度和界面形态的影响

目的:研究、比较三种脱敏剂对全酸蚀粘结剂牙本质粘结强度及其粘结界面形态的影响。方法:选择12个无龋损离体人磨牙,磨除牙合面釉质,用600目碳化硅砂纸在流水下预备出有统一玷污层的牙本质粘结面后,随机分为4组,分别用去离子水(对照组)和3种脱敏剂(Hybrid Coat、Gluma、极固宁)进行脱敏处理后,应用Single Bond 2在面粘结4 mm树脂。然后将每个牙垂直于粘结面切割出12个1.0 mm×1.0 mm×4.0 mm的粘结试件,分别在SEM下观察其粘结界面微观形态并进行微拉伸强度(μTBS)测试。结果:HybridCoat组粘结强度最高((14.81±3.87)MPa,随后依次为去离子水组(13.39±4.67)MPa、Gluma组(12.76±2.96)MPa和极固宁组(10.48±4.32)MPa,各组间两两比较,极固宁组明显低于其他3组(P﹤0.05),其他3组间相比均无显著性差异(P﹥0.05);Hybrid Coat组形成的树脂突大部分>35μm,长而密集;Gluma组形成的树脂突长7～35μm;极固宁组形成的树脂突长20～35μm,较稀疏。结论:Hybrid Coat和Gluma对全酸蚀粘结剂牙本质粘结强度无明显影响,而极固宁则明显降低其粘结强度。