颅盖骨碘伏冷冻保存后再植的临床研究

目的 探索变性自体颅骨在颅骨成形术中的应用。方法 去骨瓣减压术中所取的颅骨用无菌生理盐水洗净,碘伏浸泡,家用冰箱冰冻保存,高温高压消毒后回置。结果 16例全部成功,包括发生感染而经皮下灌洗治疗后得以保存的2例。5例皮下少量积液均自行消退,5例非筛状颅骨辩中2例,周缘有吸收,外观稍凹陷;11例筛状颅骨外形均无改变。结论 碘伏浸泡,冰冻保存,高温高压消毒的自体颅骨是一种经济、方便、安全、优良的颅骨修复材料。     

两种龋蚀检知液体外腐质检测的效果评估

目的　比较龋蚀检知液Caries detector和10% 优碘对离体牙龋坏牙体组织的检测效果,为临床应用提供实验室依据。　方法　选择有龋坏的离体牙80颗,分为Caries detector组和10% 优碘组,每组各40颗,再按龋坏深度分为Caries detector浅龋组,Caries detector深龋组,10%优碘浅龋组及10%优碘深龋组,每组20颗。分别记录各离体牙原始质量为G1,使用挖匙去腐后,再次记录各离体牙质量为G2,分别涂布Caries detector与10%优碘,使用挖匙去腐后再次记录离体牙质量为G3。观察各组腐质去除情况,计算并比较各组腐质清除率。　结果　 Caries detector或是10%优碘都有明显的染色效果,Caries detector的染色范围大于10%优碘,并且在清除染色牙本质后仍有不易移除的残留染剂在更深层的牙本质中。Caries detector浅龋组腐质清除率高于10%优碘浅龋组,差异有统计学意义（P＜0.05）; Caries detector深龋组染色后腐质清除率高于10%优碘深龋组,差异有统计学意义（P＜0.001）。　结论　Caries detector在浅龋的腐质去除上有着卓越的染色效果,但是对于患有深龋的牙齿,建议使用10%的优碘,会有较好的效果。     

碘伏消毒的临床观察——Ⅰ.术前刷手及患者皮肤消毒的效果

应用军事医学科学研究院研制的碘伏产品碘伏一号,分5组进行术前手消毒效果的观察。以常规术前酒精消毒为对照,结果表明:0.5％碘伏一号水溶液泡手及刷手效果最佳,我国应提倡大量投产此剂。     

Skuteczność antybakteryjna powidonku jodyny w próchnicy wczesnego dzieciństwa

Introduction

The generally accepted model of the prophylactic and therapeutic management of early childhood caries (ECC) and severe early childhood caries (S-ECC) does not include practices oriented to directly eliminate the causative factor: cariogenic bacteria.

“安多福”用于烧伤创面换药疗效观察

目的：研究应用新药新方法“安多福”。方法：将浅Ⅱ度深Ⅱ度烧伤患者30例随机分成两组,对照组用凡士林纱布包扎治疗,实验组用0．1％“安多福”纱布包扎治疗或者直接喷涂,对其进行临床效果分析。结果：“安多福”治疗组的分泌物与对照组相比明显减少（P〈0．05）,用药后细菌数量减少,创面愈合时间提前。结论：采用“安多福”组治疗烧伤创面方法简单,疗效显著,值得推广。     

Dilute Povidone-Iodine Solution Prevents Intraoperative Contamination of Sterile Water Basins During Total Joint Arthroplasty

BackgroundPeriprosthetic joint infection is a major complication of total joint arthroplasty (TJA). The intraoperative splash basin has been found to be a potential source of contamination. Although consensus recommendations against the use of splash basin have been made, splash basin use continues to be taught and utilized in practice. This study aims to investigate the effect of dilute betadine addition to the sterile water (SW) contents (0.02% solution) of the splash basin on contamination rates. This intervention could preserve the functionality and preferential use of the splash basin. The primary outcome of this study is the rate of splash basin contamination, with secondary outcomes of prevalence of culture speciation and mean operative times association with the rate of positive cultures.MethodsPatients undergoing primary TJA were enrolled in a randomized controlled trial with assignment to either the intervention/betadine group, in which dilute betadine was added to the standard SW splash basin, or the control/standard SW group. For a total cohort of 104 patients, a 120 mL aliquot sample of basin fluid was collected at incision (“preprocedure”) and closure (“postprocedure”). Samples were cultured and monitored for 48 hours for growth, with further testing as necessary to identify microbial speciation.ResultsOf the final 100 postprocedure samples, 0 (0.0%) were positive in the betadine group, while there were 23 (47.9%) positive samples in the SW group (P < .001). Of the positive cultures, the most common species grown were coagulase-negative Staphylococcus, Corynebacterium, and Micrococcus. The mean operative time was an average of 11 minutes longer for cases with positive cultures.ConclusionIn conclusion, treating SW splash basins with dilute povidone-iodine (0.02% solution) eliminates intraoperative contamination of splash basins in TJA procedures. This intervention is simple, low cost, and readily implementable, making it a reasonable addition to TJA protocols.Level of EvidenceLevel 1, Controlled Laboratory Study.     

牙周炎基础治疗配合PVP-I局部应用后龈沟液中GPx水平的变化

目的 :了解聚维酮碘 (PVP -I)和生理盐水配合基础治疗后龈沟液中GPx的变化和临床意义。方法 :2 3名慢性成年性牙周炎 (AP)患者 ,每一测试者选取不同象限的 1～ 2个患牙 ,总共 44颗 2 2对牙在基础治疗完成后 ,一组用 10 % (PVP -I) ,另一组用生理盐水冲洗 ,记录临床指标GI、PD、AL ,并测定治疗前后龈沟液中GPx水平。结果 :两组治疗前后临床指标均明显下降 (p <0.001) ;GPx水平明显上升 (p <0.001) ;PVP - Ⅰ组和生理盐水组 ,各临床指标和GPx水平无显著差异。结论 :AP患者基础治疗后临床指标和生化指标GPx有明显改善 ,但配合使用PVP - Ⅰ和生理盐水冲洗对GCF -GPx水平无明显改善 ,GCF -PGx可能是反映牙周组织状态的一项有意义的指标。     

聚维酮碘消毒液开瓶后持续杀菌效果观察

目的观察聚维酮碘消毒液开瓶后杀菌效果持续时间。方法采用悬液定量杀菌试验方法,对该聚维酮碘产品包装开瓶后杀菌效果持续时间进行了实验室观察。结果含有效碘5 000 mg/L的聚维酮碘消毒液原液打开包装后,在2周内可保持对含菌量107 cfu/ml菌悬液的大肠埃希菌临床株和标准株、金黄色葡萄球菌临床株和标准株等4种试验菌达到完全杀灭。含有效碘1 000 mg/L聚维酮碘消毒液原液开启包装后,能在2周内完全杀灭上述4种试验菌。结论两种浓度聚维酮碘消毒剂原液开启后可在2周内保持完全杀灭细菌繁殖体的效果不变。     

PVP-I与MEBO治疗小腿慢性感染性溃疡一例分析

目的:观察PVP-I/MEBO(聚维酮碘溶液/湿润烫伤膏)治疗小腿慢性感染性溃疡的疗效,探讨PVP-I/MEBO治疗慢性感染性溃疡的经验及医师指导跟进下家庭治疗的可行性.方法:早期换药在医院进行,每次换药后用5%PVP-I消毒创面及周边皮肤,再用MEBO厚涂溃疡面,创面敷料包扎,每天换药一次.情况改善后由患者在家自行换药,每1～2天换药一次,期间每隔一段时间来院换药一次,医师指导跟进.结果:患者从2006～2010年,右小腿多处溃疡,期间虽有反复,但最终全部治愈.结论:PVP-I/MEBO在治疗小腿慢性感染性溃疡方面,疗效可靠,经济实用,方法简易,病人乐于接受.     

聚维酮碘膜剂的制备及质量控制

目的:研制高水溶性聚维酮碘膜剂,并建立其质量控制方法。方法:用聚维酮碘、甘油、蒸馏水和水溶性成膜材料聚乙稀醇05-88制备膜剂;以电位滴定法测定聚维酮碘含量,并分别考察成品在棕色和无色玻璃瓶中的稳定性。结果:制备的膜剂完整光洁、色泽均匀、厚度一致;平均加样回收率为99.03%(RSD=0.75%);膜剂在棕色玻璃瓶中60d内外观和含量均无明显变化,而在无色玻璃瓶中含量明显降低,外观也变为淡黄色。结论:本制剂的制备工艺简便,质量控制方法准确可靠。