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Lombardo Joseph Ko Kevin Shimada Ayako Nelson Nicolas Wright Christopher Chen Jerry Maity Alisha Ruggiero Marissa L. Richard Scott Papanagnou Dimitrios Mitchell Edith Leader Amy Simone Nicole L. 《Cancer causes & control : CCC》2022,33(4):559-582
Cancer Causes & Control - A disparity exists in cancer screening rates for the Sexual and Gender Minority (SGM) community. We sought to understand the perceptions and baseline knowledge of... 相似文献
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History,Physical Examination,Laboratory Testing,and Emergency Department Ultrasonography for the Diagnosis of Acute Cholecystitis 
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Hyunjoo Lee Dimitrios Papanagnou Mitchell Berman Xiao Chi Zhang 《The Journal of emergency medicine》2019,56(4):413-416
Background
Acute infarctions of the spinal cord are rare events characterized by sudden paralysis or sensory deficits below the level of injury. Etiologies include spinal cord trauma, vascular injury, arterial dissection, thromboembolic disease, chronic inflammatory conditions, or mass effect on the spinal cord.Case Report
A 63-year-old male presented to the emergency department with sudden-onset bilateral leg numbness and weakness. His physical examination was notable for decreased light touch and temperature sensation and bilateral lower-extremity paresis. Initial magnetic resonance imaging (MRI) of his spine did not show cord injuries. Computed tomography angiography of his chest, abdomen, and pelvis demonstrated a 7.5-cm non-ruptured infrarenal abdominal aortic aneurysm (AAA) extending into bilateral iliac arteries. The patient was diagnosed with clinical spinal cord infarction secondary to a thromboembolic event from his AAA. A repeat MRI 15 h later showed spinal cord infarction from T8 down to the conus. He received an endovascular aortic repair and was ultimately discharged to rehabilitation with slightly improved lower-extremity strength.Why Should an Emergency Physician Be Aware of This?
Atraumatic cord syndrome is exceedingly rare and is associated with dissection or complication of aortic aneurysm repair. There are very few reported cases of thrombotic events leading to ischemic cord syndrome. When presented with a patient with symptoms consistent with cord syndrome in the absence of trauma or mass effect on the spinal cord, providers should work up for vascular etiology. 相似文献7.
Evangelos Terpos Maria Gavriatopoulou Ioannis Ntanasis-Stathopoulos Alexandros Briasoulis Sentiljana Gumeni Panagiotis Malandrakis Despina Fotiou Eleni-Dimitra Papanagnou Magdalini Migkou Foteini Theodorakakou Maria Roussou Evangelos Eleutherakis-Papaiakovou Nikolaos Kanellias Ioannis P. Trougakos Efstathios Kastritis Meletios A. Dimopoulos 《Blood cancer journal》2021,11(8)
Recent data suggest a suboptimal antibody response to COVID-19 vaccination in patients with hematological malignancies. Neutralizing antibodies (NAbs) against SARS-CoV-2 were evaluated in 276 patients with plasma cell neoplasms after vaccination with either the BNT162b2 or the AZD1222 vaccine, on days 1 (before the first vaccine shot), 22, and 50. Patients with MM (n = 213), SMM (n = 38), and MGUS (n = 25) and 226 healthy controls were enrolled in the study (NCT04743388). Vaccination with either two doses of the BNT162b2 or one dose of the AZD1222 vaccine leads to lower production of NAbs in patients with MM compared with controls both on day 22 and on day 50 (p < 0.001 for all comparisons). Furthermore, MM patients showed an inferior NAb response compared with MGUS on day 22 (p = 0.009) and on day 50 (p = 0.003). Importantly, active treatment with either anti-CD38 monoclonal antibodies (Mabs) or belantamab mafodotin and lymphopenia at the time of vaccination were independent prognostic factors for suboptimal antibody response following vaccination. In conclusion, MM patients have low humoral response following SARS-CoV-2 vaccination, especially under treatment with anti-CD38 or belamaf. This underlines the need for timely vaccination, possibly during a treatment-free period, and for continuous vigilance on infection control measures in non-responders.Subject terms: Myeloma, Antibodies 相似文献
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Exclusive olive oil consumption and 10‐year (2004–2014) acute coronary syndrome incidence among cardiac patients: the GREECS observational study 下载免费PDF全文
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