妊娠合并甲状腺功能亢进症110例临床分析

目的分析妊娠合并甲状腺功能亢进的治疗对妊娠结局的影响。方法将妊娠合并甲状腺功能亢进症孕妇105例分为治疗组68例和对照组37例。治疗组为妊娠期经过系统治疗且分娩前甲状腺功能基本正常者,对照组为未经正规系统的治疗或曾进行短暂治疗后自行停药在住院分娩前发现甲状腺功能显著升高者。比较2组孕妇甲状腺功能及妊娠结局。结果治疗组FT3、FT4水平明显低于对照组,TSH明显高于对照组;治疗组低体重儿（LBW）、早产、新生儿窒息、新生儿甲亢、新生儿甲减及新生儿黄疸的发生率均低于对照组,差异均有统计学意义（P〈0．05或P〈0．01）。结论妊娠合并甲亢需引起临床医师重视,加强孕妇甲状腺功能监测,积极治疗可减少孕妇和胎儿不良事件的发生。     

食管癌、贲门癌患者外周血CD+8NKT细胞活化受体NKG2D及其分泌性配体sMICA检测的临床意义

Objective To evaluate the clinical diagnostic application and operative efficacy of the expression of NKG2D in peripheral blood CD+8 NKT cell and its ligand sMICA in patients with esophageal or cardiac carcinoma.Methods The peripheral blood NKG2D positive CD+8 NKT cell percentage was concomitantly determined by flow cytometry in 53 preoperative patients including 29 postoperative patients with esophageal or cardiac carcinoma and 30 healthy controls.The serum sMICA was determined by ELISA.Results The peripheral blood NKG2D positive CD+8 NKT cell percentage in patients was significantly lower than that in controls [(77.632±8.972) % vs (89.053±6.515) %] (t = -6.113,P ＜0.05); with stage Ⅱ,Ⅲ,Ⅳ,it decreased significantly in order (F = 99.251,P ＜0.01);with lymph node metastasis lower than that without lymph node metastasis (t = -10.384,P ＜0.01); squamous carcinoma was higher than adenocarcinoma (t =9.899,P ＜0.01); postoperative was significantly higher than preoperative (t =-4.319,P ＜0.01).The level of serum sMICA in patients was significantly higher than that in controls [(326.28±85.407) pg/ml vs (210.00±92.560) pg/ml](t =7.292,P ＜0.01); with stage Ⅱ,Ⅲ,Ⅳ,it increased significautly in order (F =63.355,P ＜0.01); with lymph node metastasis higher than that without lymph node metastasis (t =7.770,P ＜0.01); squamous carcinoma was lower than adenocarcinoma (t =-7.593,P＜0.01); postoperative was significantly lower than preoperative (t =7.027,P ＜0.01).Serum sMICA could inhibit peripheral blood CD+8 NKT cell activation receptor NKG2D (F =142.773,P ＜0.05),determination coefficient R2 = 0.7368.Conclusion The level of peripheral blood CD+8NKT cell activation receptor NKG2D and serum sMICA in patients could be an assistant indicator for     

Arnold-Chiari畸形合并脊髓空洞症的显微手术治疗

目的探讨Arnold-Chiari畸形合并脊髓空洞症（ACM-SM）的手术方式和疗效。方法对2006年1月-2008年12月收治的23例ACM-SM患者采用后颅窝减压、硬膜成形、枕大池重建术,并根据不同的临床特点行下疝扁桃体切除及脊髓中央管口疏通术。结果所有患者随访6个月-2年,症状消失和改善21例,仅2例症状恶化。所有患者中有17例来本院复查MRI,示枕大池形成14例,脊髓空洞缩小12例。结论解除后脑受压,恢复脑脊液的生理循环状态,消除空洞对脊髓的压迫、侵害,这是手术治疗ACM-SM的关键。     

B超诊断婴幼儿肠套叠

Ｂ超诊断婴幼儿肠套叠（１０２８００）河北省廊坊市人民医院Ｂ超室石秀玲，田志华，王光珍１９９４年１月至１９９５年１２月，我们采用Ｂ超检查诊断婴幼儿肠套叠８例，并经低压灌肠复位或手术治疗证实，现报告如下。１临床资料１．１资料：本组８例，男５例，女３例；年...     

多技术联合在丘脑胶质瘤显微手术治疗中的应用

丘脑胶质瘤毗邻第三脑室、下丘脑、内囊等大脑重要结构,是一种具有致残率高、手术难度大等特点的颅内肿瘤疾病[1],患者多有抑郁、精神呆滞、颅内压增高等问题,手术不当易致人死亡。鉴于此,本院以锥体束导航结合术中高场强磁共振技术辅助完成丘脑胶质瘤显微手术,其中锥体束导航可减少患者大脑功能结构的损伤[2],而高场强磁共振技术则能够对肿瘤切除程度进行实时反馈,两者辅助下行相应显微手术能够稳定提高丘脑胶质瘤患者的手术疗效[3]。本研究探讨丘脑胶质瘤患者应用以上技术实施显微手术的实际效用,报告如下。     

甘草散结合针刺治疗小儿遗尿47例

目的:观察药针结合治疗小儿遗尿的疗效。方法:采用自拟甘草散(甘草、硫磺、紫河车、菖蒲、桑螵蛸、金樱子),结合针刺大钟、通里、三阴交、关元(艾灸)治疗本病47例。结果:总有效率为93.7%。结论:此疗法具有醒神开窍、理肺健脾、壮阳补肾之功效。     

肝气虚证治初探

后世言＂肝无补法＂见肝之病必先实脾,究非《灵素》本旨,且未尽合临床,值得探讨.     

妊娠合并甲状腺功能亢进症不同控制状态对孕妇及新生儿的影响

甲状腺功能亢进是甲状腺分泌过多甲状腺素或血循环中甲状腺激素水平增高的一组常见内分泌疾病。妊娠合并甲状腺功能亢进对孕产妇和胎儿均有不良的影响。妊娠期甲状腺功能亢进得到及时、适当的治疗后,病情均会得到有效的控制,能确保母婴的安全。对于中、重症甲状腺功能亢进未得到及时、有效控制的产妇,其妊娠结局不容乐观,出现甲状腺功能亢进危象是最为严重的结果。