全文获取类型
收费全文 | 31348篇 |
免费 | 2358篇 |
国内免费 | 497篇 |
专业分类
耳鼻咽喉 | 633篇 |
儿科学 | 532篇 |
妇产科学 | 703篇 |
基础医学 | 4411篇 |
口腔科学 | 505篇 |
临床医学 | 2604篇 |
内科学 | 7044篇 |
皮肤病学 | 953篇 |
神经病学 | 2162篇 |
特种医学 | 1757篇 |
外科学 | 4246篇 |
综合类 | 531篇 |
一般理论 | 15篇 |
预防医学 | 1269篇 |
眼科学 | 908篇 |
药学 | 2775篇 |
中国医学 | 337篇 |
肿瘤学 | 2818篇 |
出版年
2023年 | 175篇 |
2022年 | 124篇 |
2021年 | 839篇 |
2020年 | 498篇 |
2019年 | 819篇 |
2018年 | 949篇 |
2017年 | 684篇 |
2016年 | 910篇 |
2015年 | 1268篇 |
2014年 | 1494篇 |
2013年 | 1739篇 |
2012年 | 2464篇 |
2011年 | 2537篇 |
2010年 | 1537篇 |
2009年 | 1320篇 |
2008年 | 1852篇 |
2007年 | 1794篇 |
2006年 | 1594篇 |
2005年 | 1532篇 |
2004年 | 1285篇 |
2003年 | 1244篇 |
2002年 | 1134篇 |
2001年 | 751篇 |
2000年 | 681篇 |
1999年 | 628篇 |
1998年 | 239篇 |
1997年 | 227篇 |
1996年 | 195篇 |
1995年 | 192篇 |
1994年 | 167篇 |
1993年 | 111篇 |
1992年 | 312篇 |
1991年 | 240篇 |
1990年 | 272篇 |
1989年 | 274篇 |
1988年 | 257篇 |
1987年 | 207篇 |
1986年 | 185篇 |
1985年 | 168篇 |
1984年 | 147篇 |
1983年 | 120篇 |
1982年 | 87篇 |
1981年 | 75篇 |
1980年 | 76篇 |
1979年 | 124篇 |
1978年 | 81篇 |
1977年 | 67篇 |
1976年 | 53篇 |
1975年 | 62篇 |
1974年 | 53篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
1.
Kevin Kyung Ho Choi Santosh Sanagapalli 《World journal of gastrointestinal oncology》2022,14(3):568-586
Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC). Progression to cancer typically occurs in a stepwise fashion through worsening dysplasia and ultimately, invasive neoplasia. Established EAC with deep involvement of the esophageal wall and/or metastatic disease is invariably associated with poor long-term survival rates. This guides the rationale of surveillance of Barrett’s in an attempt to treat lesions at an earlier, and potentially curative stage. The last two decades have seen a paradigm shift in management of Barrett’s with rapid expansion in the role of endoscopic eradication therapy (EET) for management of dysplastic and early neoplastic BE, and there have been substantial changes to international consensus guidelines for management of early BE based on evolving evidence. This review aims to assist the physician in the therapeutic decision-making process with patients by comprehensive review and summary of literature surrounding natural history of Barrett’s by histological stage, and the effectiveness of interventions in attenuating the risk posed by its natural history. Key findings were as follows. Non-dysplastic Barrett’s is associated with extremely low risk of progression, and interventions cannot be justified. The annual risk of cancer progression in low grade dysplasia is between 1%-3%; EET can be offered though evidence for its benefit remains confined to highly select settings. High-grade dysplasia progresses to cancer in 5%-10% per year; EET is similarly effective to and less morbid than surgery and should be routinely performed for this indication. Risk of nodal metastases in intramucosal cancer is 2%-4%, which is comparable to operative mortality rate, so EET is usually preferred. Submucosal cancer is associated with nodal metastases in 14%-41% hence surgery remains standard of care, except for select situations. 相似文献
2.
Journal of Public Health - The first Covid-19 cases were reported in Malaysia on 25 January 2019 followed by a quiescent period before an upward swing of the cases at the end of February 2020,... 相似文献
3.
4.
Babiker Hani M. Milhem Mohammed Aisner Joseph Edenfield William Shepard Dale Savona Michael Iyer Swaminathan Abdelrahim Maen Beach C. L. Skikne Barry Laille Eric Tsai Kao-Tai Ho Thai 《Cancer chemotherapy and pharmacology》2020,85(3):621-626
Cancer Chemotherapy and Pharmacology - CC-486 is an oral formulation of azacitidine that allows for extended dosing schedules to prolong azacitidine exposure to malignant cells and maximize... 相似文献
5.
Anita Ho 《The Hastings Center report》2019,49(1):36-39
From predicting medical conditions to administering health behavior interventions, artificial intelligence technologies are being developed to enhance patient care and outcomes. However, as Mélanie Terrasse and coauthors caution in an article in this issue of the Hastings Center Report, an overreliance on virtual technologies may depersonalize medical interactions and erode therapeutic relationships. The increasing expectation that patients will be actively engaged in their own care, regardless of the patients’ desire, technological literacy, and economic means, may also violate patients’ autonomy and exacerbate access. Moreover, since AI design is both a technical and social process, algorithms may mirror human biases, calling into question the vision of AI technologies surpassing human judgment and avoiding prejudices in decision‐making. The best answer to these problems is to develop AI health technologies as part of a culture of health care quality improvement, responding to existing needs while being proactive about potential technical and ethical problems that can arise from the technologies’ design and implementation. 相似文献
6.
Min Hee Hong MD Seong Gu Heo PhD Yun-Gyoo Lee MD PhD Hyo Song Kim MD PhD Keon Uk Park MD PhD Hoon-Gu Kim MD PhD Yoon Ho Ko MD PhD Ik-Joo Chung MD PhD Young Joo Min MD PhD Min Kyoung Kim MD PhD Kyu Ryung Kim PhD Jinseon Yoo MS Tae-Min Kim MD PhD Hye Ryun Kim MD PhD Byoung Chul Cho MD PhD 《Cancer》2020,126(20):4521-4531
7.
Ashton A. Connor Robert E. Denroche Gun Ho Jang Mathieu Lemire Amy Zhang Michelle Chan-Seng-Yue Gavin Wilson Robert C. Grant Daniele Merico Ilinca Lungu John M.S. Bartlett Dianne Chadwick Sheng-Ben Liang Jenna Eagles Faridah Mbabaali Jessica K. Miller Paul Krzyzanowski Heather Armstrong Steven Gallinger 《Cancer cell》2019,35(2):267-282.e7
8.
9.
10.