首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   42576篇
  免费   2058篇
  国内免费   320篇
耳鼻咽喉   314篇
儿科学   783篇
妇产科学   487篇
基础医学   5620篇
口腔科学   1227篇
临床医学   2524篇
内科学   11014篇
皮肤病学   1028篇
神经病学   2855篇
特种医学   1521篇
外科学   7484篇
综合类   143篇
一般理论   1篇
预防医学   1226篇
眼科学   739篇
药学   2607篇
中国医学   132篇
肿瘤学   5249篇
  2023年   210篇
  2022年   184篇
  2021年   876篇
  2020年   529篇
  2019年   729篇
  2018年   964篇
  2017年   755篇
  2016年   879篇
  2015年   919篇
  2014年   1210篇
  2013年   1544篇
  2012年   2478篇
  2011年   2887篇
  2010年   1634篇
  2009年   1354篇
  2008年   2529篇
  2007年   2777篇
  2006年   2580篇
  2005年   2776篇
  2004年   2696篇
  2003年   2642篇
  2002年   2697篇
  2001年   628篇
  2000年   576篇
  1999年   634篇
  1998年   581篇
  1997年   451篇
  1996年   432篇
  1995年   429篇
  1994年   390篇
  1993年   363篇
  1992年   466篇
  1991年   411篇
  1990年   366篇
  1989年   402篇
  1988年   352篇
  1987年   322篇
  1986年   311篇
  1985年   271篇
  1984年   220篇
  1983年   177篇
  1982年   116篇
  1981年   123篇
  1980年   118篇
  1979年   138篇
  1978年   92篇
  1977年   77篇
  1976年   55篇
  1975年   64篇
  1973年   58篇
排序方式: 共有10000条查询结果,搜索用时 718 毫秒
1.
2.
3.
4.
5.
6.
7.
BackgroundThe “retired husband syndrome” refers to the negative impact of the husband’s retirement on the wife’s health. This study provided new insights by examining whether and to what extent the wife’s social participation, interactions with her husband, and job status prior to her husband’s retirement affected the evolution of her mental health after her husband’s retirement.MethodsWe collected data from a 12-wave nationwide panel survey conducted from 2005 to 2016, starting with individuals aged 50–59 years. Focusing on 3,794 female respondents whose husbands retired during the survey period, we applied random-effects linear regression models to investigate the evolution of their mental health as measured by the Kessler 6 (K6) score (range, 0–24; Mean, 3.41; standard deviation, 4.11) during the 5 years after their husbands’ retirement.ResultsOn average, the wife’s K6 score rose by 0.18 (95% confidence interval [CI], 0.08–0.28), 0.18 (95% CI, 0.03–0.34), and 0.19 (95% CI, −0.02 to 0.43) in the first 3 years, respectively, after the husband’s retirement, before declining toward the baseline level. However, the wife’s active social participation, intense interactions with her husband, and absence of paid employment before her husband’s retirement prevented her mental health from deteriorating.ConclusionThe results suggest the limited relevance of the “retired husband syndrome” among middle-aged Japanese couples. The effects of a husband’s retirement on the wife’s mental health depended heavily on her prior behavior.Key words: marital quality, mental health, random-effects model, retired husband syndrome, social participation  相似文献   
8.
Objectives: Phase angle (PA) is a poor prognostic factor in patients with advanced cancer. This study aimed to identify possible correlations between PA and symptoms, quality of life, fluid retention, and laboratory data in cancer patients in palliative care settings.

Methods: Individuals who visited the outpatient clinic or were admitted to the palliative care unit were eligible. Patients with a performance status of 4 and/or those unable to complete questionnaires were excluded. PA was evaluated using a bioanalyzer device. The correlation coefficient between PA and the variables of interest was analyzed.

Results: A total of 102 patients were analyzed. PA was weakly correlated with age (ρ = ?0.22), performance status (ρ = ?0.30), functional well-being (ρ?=?0.20), anorexia/cachexia subscale (ρ?=?0.22), and Functional Assessment of Anorexia/Cachexia Therapy trial outcome index (ρ?=?0.26). PA was also correlated with fluid retention (ρ = ?0.34) and albumin (ρ?=?0.32), C-reactive protein (ρ = ?0.31), and hemoglobin (ρ?=?0.41) levels. Sub-analysis stratified according to sex revealed that males demonstrated the same results; however, female sex demonstrated a correlation between PA and social well-being (ρ = ?0.43).

Conclusions: PA was correlated with physical condition, but not with psychological well-being.  相似文献   

9.

Purpose

To evaluate the influence of percutaneous cryoablation for renal cell carcinoma on function of the affected kidney.

Materials and Methods

Between June 2016 and September 2017 at our institution, 12 inoperable patients underwent 15 cryoablation sessions for 17 small renal tumors. Of these, 9 patients who underwent 11 sessions of cryoablation were the focus of this study. For those patients, time-dependent changes in postoperative renal function were investigated by a retrospective review of clinical records. Evaluated were the estimated glomerular filtration rate (eGFR) and scintigraphy using 99m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before and 1 week, 1–2 months, and more than 6 months after cryoablation.

Results

Mean baseline eGFR was 76.88 ± 29.82 mL/min/1.73 m2 (mean ± standard deviation; range, 23.4–112.5). Mean eGFR 1 week, 1–2 months, and more than 6 months after cryoablation were 74.56 ± 26.68 mL/min/1.73 m2 (21.0–101.1), 69.5 ± 25.28 mL/min/1.73 m2 (24.1–105.6), and 75.08 ± 26.25 mL/min/1.73 m2 (29.0–107.3), respectively. Changes were statistically insignificant (P = .6044, P = .6699, and P = .9038, respectively). Regarding split renal function, the mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 47.27% ± 6.14 (38.8%–57.0%). Mean contributions of the affected kidney 1 week after, 1–2 months after, and more than 6 months after cryoablation were 44.40% ± 5.37 (38.3%–53.6%), 44.57% ± 6.52 (34.35%–55.0%), and 45.41% ± 7.77 (34.4%–56.5%), respectively. Differences from baseline were significant for the earliest 2 periods (P = .0473 and P = .0334, respectively) but not the later period (P = .2532).

Conclusions

Results suggested that total renal function does not worsen after cryoablation; however, function of the affected kidney worsened after cryoablation but later partially recovered.  相似文献   
10.
Although rheumatologists, neurologists and dermatologists see patients with polymyositis (PM) and dermatomyositis (DM), their management appears to vary depending on the physician's specialty. The aim of the present study was to establish the treatment consensus among specialists of the three fields to standardize the patient care. We formed a research team supported by a grant from the Ministry of Health, Labor and Welfare, Japan. Clinical questions (CQ) on the management of PM and DM were raised. A published work search on CQ was performed primarily using PubMed. Using the nominal group technique, qualified studies and results in the published work were evaluated and discussed to reach consensus recommendations. They were sent out to the Japan College of Rheumatology, Japanese Society of Neurology and Japanese Dermatological Association for their approval. We reached a consensus in 23 CQ and made recommendations and a decision tree for management was proposed. They were officially approved by the three scientific societies. In conclusion, a multidisciplinary treatment consensus for the management of PM and DM was established for the first time.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号