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Effects of enteral nutrition and parenteral nutrition on survival in patients with advanced cancer cachexia: Analysis of a multicenter prospective cohort study
Authors:Koji Amano  Isseki Maeda  Hiroto Ishiki  Tomofumi Miura  Yutaka Hatano  Hiroaki Tsukuura  Tomohiko Taniyama  Yoshihisa Matsumoto  Yosuke Matsuda  Hiroyuki Kohara  Tatsuya Morita  Masanori Mori
Institution:11. Seirei Hospice, Seirei Mikatahara General Hospital, Japan;12. Department of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Japan;13. Department of Palliative Care, Miyazaki Medical Association Hospital, Japan;14. Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Japan;15. Department of Oncology and Palliative Medicine, Mitsubishi Kyoto Hospital, Japan;p. Department of Respiratory Surgery, Mitsubishi Kyoto Hospital, Japan;q. Hiroshima Prefectural Hospital, Japan;r. Department of Palliative Care, Tokyo Metropolitan Cancer & Infectious Diseases Center Komagome Hospital, Japan;s. Department of Palliative Care, NTT Medical Center Tokyo, Japan;t. Home Care Clinic Aozora Shin-Matsudo, Japan;u. Department of Palliative Medicine, Osaka City General Hospital, Japan;v. Aso Iizuka Hospital/Transitional and Palliative Care, Japan;w. Japan Community Health Care Organization Kyushu Hospital/Palliative Care, Japan;x. Inoue Hospital/Internal Medicine, Japan;y. Department of General Internal Medicine, Aso Iizuka Hospital, Japan;z. Department of Emergency Medicine, Osaka Red Cross Hospital, Japan;11. Department of Transitional and Palliative Care, Aso Iizuka Hospital, Japan;12. Immuno-Rheumatology Center, St Luke''s International Hospital, Japan;13. Department of Cardiology, Aso Iizuka Hospital, Japan;14. Department of Orthopedic Surgery, Saga-Ken Medical Centre Koseikan, Japan;15. Environmental Health and Safety Division, Environmental Health Department, Ministry of the Environment, Japan;16. TOSHIBA, Japan;17. Department of Hematology/Oncology, Japan Community Healthcare Organization Kyushu Hospital, Japan;18. Oshima Clinic, Japan;19. Department of Palliative Medicine, Kobe University School of Medicine, Japan;110. Department of Palliative Medicine, Kobe University Graduate School of Medicine, Japan;111. Division of Palliative Care, Konan Medical Center, Japan;112. Hospice, The Japan Baptist Hospital, Japan;113. Department of Palliative Medicine, Tohoku University School of Medicine, Japan;114. Department of Biostatistics, Tohoku University Graduate School of Medicine, Japan;115. Department of Palliative Nursing, Health Sciences, Tohoku University Graduate School of Medicine, Japan;1p. Graduate School of Education, Tohoku University, Japan;1q. Department of Palliative Care, Komaki City Hospital, Japan;1r. Department of Palliative Care, Japanese Red Cross Medical Center, Japan;1s. Hospice, Yodogawa Christian Hospital, Japan;1t. Department of Palliative Care Internal Medicine, Osaka General Hospital of West Japan Railway Company, Japan;1u. Okoshi Nagominomori Clinic, Japan;1v. Kawasaki Municipal Ida Hospital, Kawasaki Comprehensive Care Center, Japan;1w. Department of Palliative Medicine, National Cancer Center Hospital East, Japan;1x. Department of Palliative Medicine, Tsukuba Medical Center Hospital, Japan;1y. Department of General Medicine and Primary Care, Palliative Care Team, University of Tsukuba Hospital, Japan;1z. Department of Palliative Medicine, Yuai Memorial Hospital, Japan;21. Department of Clinical Oncology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Japan;22. Department of Internal Medicine, Palliative Care, Medical Hospital, Tokyo Medical and Dental University, Japan;23. Department of Palliative Care Unit, JCHO Tokyo Shinjuku Medical Center, Japan;24. Department of Palliative Medicine, Suita Tokushukai Hospital, Japan;25. Department of Palliative Medicine, National Cancer Center Hospital, Japan;26. Department of Hospice Palliative Care, Eikoh Hospital, Japan;27. Department of Palliative Care, Fukuoka Minato Home Medical Care Clinic, Japan;28. Eiju General Hospital, Japan;29. Faculty of Medicine, University of Tsukuba, Japan;210. Tokyo University of Pharmacy and Life Sciences, Department of Practical Pharmacy, Japan;211. Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Japan;212. Hospice, Ise Municipal General Hospital, Japan;213. Department of Anesthesiology & Intensive Care Medicine/Osaka University Graduate School of Medicine, Japan;214. Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Japan;215. Department of Palliative Medicine, Kyoto University Hospital, Japan;2p. Palliative Care Team, and Palliative and Supportive Care, National Kyushu Cancer Center, Japan;1. Department of Palliative Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan;2. Department of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute City, Aichi 480-1195, Japan;3. Department of Palliative Care, Senri-chuo Hospital, 1-4-3 Shinsenrihigashi-machi, Toyonaka City, Osaka 560-0082, Japan;4. Department of Palliative Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa City, Chiba 277-8577, Japan;5. Department of Palliative Care, Kyowakai Medical Corporation, Daini Kyoritsu Hospital, 5-28 Sakaemachi, Kawanishi City, Hyogo 666-0033, Japan;6. Seirei Hospice, Seirei Mikatahara General Hospital, 3453 Mikatahara-cho, Kita-ku, Hamamatsu City, Shizuoka 433-8558, Japan;7. Department of Oncology and Palliative Medicine, Mitsubishi Kyoto Hospital, 1 Katsuragosyo-cho, Nishikyo-ku, Kyoto City, Kyoto 615-8087, Japan;8. Palliative Care Department, St. Luke''s International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, Japan;9. Department of Palliative Care, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Minami-ku, Hiroshima City, Hiroshima 734-8530, Japan;10. Palliative and Supportive Care Division, Seirei Mikatahara General Hospital, 3453 Mikatahara-cho, Kita-ku, Hamamatsu City, Shizuoka, 433-8558, Japan;1. Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan;2. Department of Hepato-Pancreato-Biliary Surgery, National Liver Institute, Menoufia University, Egypt;3. Department of Gastroenterological and General Surgery, St. Luke''s International Hospital, Tokyo, Japan;1. Division of Endocrinology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil;2. Department of Social Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil;3. Division of Endocrinology, Faculdade de Medicina, Instituto de Ciências da Saúde,Universidade Federal do Pará, Belém, PA, Brazil;1. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK;2. Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden;3. Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK;1. Division of Nephrology, Tagawa Municipal Hospital, Fukuoka, Japan;2. Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;3. Fukuoka Renal Clinic, Fukuoka, Japan;4. Department of Internal Medicine, Fukuoka Dental College, Fukuoka, Japan;5. Department of Nephrology, Nara Medical University, Nara, Japan
Abstract:
Keywords:Enteral nutrition  Parenteral nutrition  Nutritional support  Palliative care  Cancer cachexia  EN"}  {"#name":"keyword"  "$":{"id":"kwrd0040"}  "$$":[{"#name":"text"  "_":"enteral nutrition  PNH"}  {"#name":"keyword"  "$":{"id":"kwrd0050"}  "$$":[{"#name":"text"  "_":"parenteral nutrition and hydration  ECOG PS"}  {"#name":"keyword"  "$":{"id":"kwrd0060"}  "$$":[{"#name":"text"  "_":"Eastern Cooperative Oncology Group Performance Status  IPOS"}  {"#name":"keyword"  "$":{"id":"kwrd0070"}  "$$":[{"#name":"text"  "_":"Integrated Palliative care Outcome Scale  CPS"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"clinical predictions of survival  QOL"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"quality of life  HRs"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"hazard ratios  CIs"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"confidence intervals
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