全文获取类型
收费全文 | 944404篇 |
免费 | 69400篇 |
国内免费 | 2476篇 |
专业分类
耳鼻咽喉 | 13124篇 |
儿科学 | 24558篇 |
妇产科学 | 23459篇 |
基础医学 | 134155篇 |
口腔科学 | 28594篇 |
临床医学 | 82420篇 |
内科学 | 184445篇 |
皮肤病学 | 19426篇 |
神经病学 | 72642篇 |
特种医学 | 37375篇 |
外国民族医学 | 82篇 |
外科学 | 153663篇 |
综合类 | 21373篇 |
现状与发展 | 5篇 |
一般理论 | 240篇 |
预防医学 | 62708篇 |
眼科学 | 21726篇 |
药学 | 74098篇 |
26篇 | |
中国医学 | 3368篇 |
肿瘤学 | 58793篇 |
出版年
2018年 | 9594篇 |
2017年 | 7571篇 |
2016年 | 8285篇 |
2015年 | 9605篇 |
2014年 | 12832篇 |
2013年 | 18440篇 |
2012年 | 25455篇 |
2011年 | 26465篇 |
2010年 | 15835篇 |
2009年 | 15156篇 |
2008年 | 25721篇 |
2007年 | 26791篇 |
2006年 | 27558篇 |
2005年 | 26360篇 |
2004年 | 25257篇 |
2003年 | 24257篇 |
2002年 | 23714篇 |
2001年 | 55118篇 |
2000年 | 56911篇 |
1999年 | 47144篇 |
1998年 | 10502篇 |
1997年 | 9185篇 |
1996年 | 9290篇 |
1995年 | 9062篇 |
1994年 | 8385篇 |
1993年 | 7644篇 |
1992年 | 35572篇 |
1991年 | 34006篇 |
1990年 | 32796篇 |
1989年 | 31916篇 |
1988年 | 29042篇 |
1987年 | 28289篇 |
1986年 | 26315篇 |
1985年 | 25172篇 |
1984年 | 17841篇 |
1983年 | 15137篇 |
1982年 | 7779篇 |
1981年 | 6750篇 |
1979年 | 15779篇 |
1978年 | 10590篇 |
1977年 | 9037篇 |
1976年 | 7865篇 |
1975年 | 8621篇 |
1974年 | 10456篇 |
1973年 | 9857篇 |
1972年 | 9361篇 |
1971年 | 8852篇 |
1970年 | 8417篇 |
1969年 | 7918篇 |
1968年 | 7202篇 |
排序方式: 共有10000条查询结果,搜索用时 187 毫秒
1.
2.
3.
Malou A.H. Nuijten Thijs M.H. Eijsvogels Valerie M. Monpellier Ignace M.C. Janssen Eric J. Hazebroek Maria T.E. Hopman 《Obesity reviews》2022,23(1):e13370
Postbariatric loss of muscle tissue could negatively affect long-term health due to its role in various bodily processes, such as metabolism and functional capacity. This meta-analysis aimed to unravel time-dependent changes in the magnitude and progress of lean body mass (LBM), fat-free mass (FFM), and skeletal muscle mass (SMM) loss following bariatric surgery. A systematic literature search was conducted in Pubmed, Embase, and Web of Science. Fifty-nine studies assessed LBM (n = 37), FFM (n = 20), or SMM (n = 3) preoperatively and ≥1 time points postsurgery. Random-effects meta-analyses were performed to determine pooled loss per outcome parameter and follow-up time point. At 12-month postsurgery, pooled LBM loss was ?8.13 kg [95%CI ?9.01; ?7.26]. FFM loss and SMM loss were ?8.23 kg [95%CI ?10.74; ?5.73] and ?3.18 kg [95%CI ?5.64; ?0.71], respectively. About 55% of 12-month LBM loss occurred within 3-month postsurgery, followed by a more gradual decrease up to 12 months. Similar patterns were seen for FFM and SMM. In conclusion, >8 kg of LBM and FFM loss was observed within 1-year postsurgery. LBM, FFM, and SMM were predominantly lost within 3-month postsurgery, highlighting that interventions to mitigate such losses should be implemented perioperatively. 相似文献
4.
S. Harrogate J. Barnes K. Thomas A. Isted G. Kunst S. Gupta S. Rudd T. Banerjee R. Hinchliffe R. Mouton 《Anaesthesia》2023,78(11):1393-1408
Tobacco smoking is associated with a substantially increased risk of postoperative complications. The peri-operative period offers a unique opportunity to support patients to stop tobacco smoking, avoid complications and improve long-term health. This systematic review provides an up-to-date summary of the evidence for tobacco cessation interventions in surgical patients. We conducted a systematic search of randomised controlled trials of tobacco cessation interventions in the peri-operative period. Quantitative synthesis of the abstinence outcomes data was by random-effects meta-analysis. The primary outcome of the meta-analysis was abstinence at the time of surgery, and the secondary outcome was abstinence at 12 months. Thirty-eight studies are included in the review (7310 randomised participants) and 26 studies are included in the meta-analysis (5969 randomised participants). Studies were pooled for subgroup analysis in two ways: by the timing of intervention delivery within the peri-operative period and by the intensity of the intervention protocol. We judged the quality of evidence as moderate, reflecting the degree of heterogeneity and the high risk of bias. Overall, peri-operative tobacco cessation interventions increased successful abstinence both at the time of surgery, risk ratio (95%CI) 1.48 (1.20–1.83), number needed to treat 7; and 12 months after surgery, risk ratio (95%CI) 1.62 (1.29–2.03), number needed to treat 9. More work is needed to inform the design and optimal delivery of interventions that are acceptable to patients and that can be incorporated into contemporary elective and urgent surgical pathways. Future trials should use standardised outcome measures. 相似文献
5.
目的分析细棒、PEEK棒固定对寰枢关节稳定性的影响。方法采用6具新鲜成人枕骨(occipital bone,Oc)~颈椎C4节段进行测试,模拟以下手术及固定状态:①完整状态;②损伤状态:枢椎齿状突II型骨折;③坚强固定:寰枢椎均采用普通椎弓根螺钉固定,直径3.5 mm钛棒连接;④PEEK棒:直径3.5 mm的PEEK棒连接;⑤细棒:直径2.0 mm钛棒连接。采用重复测量实验设计,在完整、损伤和不同的固定状态下,通过脊柱试验机对标本分别施加1.5 N·m的前屈/后伸、左/右侧弯和左/右轴向旋转的纯力偶矩。采用Optotrak三维运动测量系统连续采集标本运动,分析寰枢椎之间角度运动范围和中性区。结果采用直径3.5 mm的钛棒,2.0 mm的细棒以及3.5 mm的PEEK棒固定后,在前屈、后伸、侧弯和旋转方向上均显著减小了固定节段的运动范围(P<0.05)。直径3.5 mm和2.0 mm的棒固定后的运动范围,在各个方向上无显著性差异。PEEK棒固定的运动范围仅在侧弯方向上大于坚强固定(P=0.005),其他方向无显著性差异。3种固定方式在屈伸、侧弯和旋转方向上均显著减小了固定节段的中性区(P<0.05)。各种固定方式之间相比较,无显著性差异(P>0.05)。结论在寰枢关节采用直径2.0 mm的细棒固定,与坚强固定的稳定性相当。采用直径3.5 mm的PEEK棒固定,在前屈、后伸、旋转方向上与坚强固定的稳定性相当,在侧弯方向上弱于坚强固定。 相似文献
6.
Li Dong Mari Nygård Nathalie C. Støer Ole Klungsøyr Bo T. Hansen 《International journal of cancer. Journal international du cancer》2023,153(2):399-406
Human papillomavirus (HPV) vaccine effectiveness may differ between settings. Here we present the first real-world effectiveness study of HPV vaccination on high-grade cervical lesions from Norway, among women who received HPV vaccine outside the routine program. We performed an observational study of all Norwegian women born 1975 to 1996 and retrieved individual data from nationwide registries on HPV vaccination status and incidence of histologically verified high-grade cervical neoplasia during 2006 to 2016. We estimated the incidence rate ratio (IRR) and 95% confidence intervals (CI) for vaccination vs no vaccination by Poisson regression stratified by age at vaccination <20 years and ≥20 years. The cohort consisted of 832 732 women, of which 46 381 (5.6%) received at least one dose of HPV vaccine by the end of 2016. The incidence rate of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) increased with age regardless of vaccination status and was highest at age 25 to 29, at 637/100 000 among unvaccinated women, 487/100 000 among women vaccinated before age 20 and 831/100 000 among women vaccinated at age 20 or older. The adjusted IRR of CIN2+ between vaccinated and unvaccinated women was 0.62 (95% CI: 0.46-0.84) for women vaccinated below age 20, and 1.22 (95% CI: 1.03-1.43) for women vaccinated at age 20 or older. These findings indicate that HPV vaccination among women too old to be eligible for routine HPV vaccination is effective among women who are vaccinated below age 20 but may not have the desired impact among women who are vaccinated at age 20 or older. 相似文献
7.
8.
9.
10.
Paulmurugan Ramasamy Malhotra Meenakshi Massoud Zahra T. Massoud Tarik F. 《Journal of molecular medicine (Berlin, Germany)》2022,100(7):1093-1093
Journal of Molecular Medicine - 相似文献