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排序方式: 共有527条查询结果,搜索用时 250 毫秒
1.
David Cahn Elliot Courter Gregory Diorio Michael Metro Phillip Ginsberg 《Current Urology》2015,8(2):101-103
Priapism is defined as an erection lasting for more than 4 hours and can be grouped into 3 distinct subtypes: ischemic (low-flow), stuttering and non-ischemic (high-flow). Herein, we present an interesting case of conversion from a low-flow to high-flow priapism after a distal shunting procedure. This is a rare phenomenon that has a paucity of documented cases. Diagnosis requires prompt clinical suspicion and confirmatory testing including penile cavernosal blood gases and Doppler ultrasound.Key Words: Priapism, Ischemic priapism, Non-Ischemic priapism 相似文献
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Alena Svatkova René C.W. Mandl Thomas W. Scheewe Wiepke Cahn René S. Kahn Hilleke E. Hulshoff Pol 《Schizophrenia bulletin》2015,41(4):869-878
It has been shown that learning a new skill leads to structural changes in the brain. However, it is unclear whether it is the acquisition or continuous practicing of the skill that causes this effect and whether brain connectivity of patients with schizophrenia can benefit from such practice. We examined the effect of 6 months exercise on a stationary bicycle on the brain in patients with schizophrenia and healthy controls. Biking is an endemic skill in the Netherlands and thus offers an ideal situation to disentangle the effects of learning vs practice. The 33 participating patients with schizophrenia and 48 healthy individuals were assigned to either one of two conditions, ie, physical exercise or life-as-usual, balanced for diagnosis. Diffusion tensor imaging brain scans were made prior to and after intervention. We demonstrate that irrespective of diagnosis regular physical exercise of an overlearned skill, such as bicycling, significantly increases the integrity, especially of motor functioning related, white matter fiber tracts whereas life-as-usual leads to a decrease in fiber integrity. Our findings imply that exercise of an overlearned physical skill improves brain connectivity in patients and healthy individuals. This has important implications for understanding the effect of fitness programs on the brain in both healthy subjects and patients with schizophrenia. Moreover, the outcome may even apply to the nonphysical realm.Key words: physical exercise, schizophrenia, diffusion tensor imaging, connectivity, longitudinal, fractional anisotropy 相似文献
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Suzanne Medema Roel J. T. Mocking Maarten W. J. Koeter Frédéric M. Vaz Carin Meijer Lieuwe de Haan Nico J. M. van Beveren for GROUPa; aGenetic Risk Outcome of Psychosis investigators: René Kahn Lieuwe de Haan Jim van Os Durk Wiersma Richard Bruggeman Wiepke Cahn Carin Meijer Inez Myin-Germeys 《Schizophrenia bulletin》2016,42(2):358-368
Background: Two recent meta-analyses showed decreased red blood cell (RBC) polyunsaturated fatty acids (FA) in schizophrenia and related disorders. However, both these meta-analyses report considerable heterogeneity, probably related to differences in patient samples between studies. Here, we investigated whether variations in RBC FA are associated with psychosis, and thus may be an intermediate phenotype of the disorder. Methods: For the present study, a total of 215 patients (87% outpatients), 187 siblings, and 98 controls were investigated for multiple FA analyses. Based on previous studies, we investigated docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), arachidonic acid (AA), linoleic acid (LA), nervonic acid (NA), and eicasopentaenoic acid (EPA). On an exploratory basis, a large number of additional FA were investigated. Multilevel mixed models were used to compare the FA between the 3 groups. Results: Compared to controls, both patients and siblings showed significantly increased DHA, DPA, AA, and NA. LA was significantly higher in siblings compared to controls. EPA was not significantly different between the 3 groups. Also the exploratory FA were increased in patients and siblings. Conclusions: We found increased RBC FA DHA, DPA, AA, and NA in patients and siblings compared to controls. The direction of change is similar in both patients and siblings, which may suggest a shared environment and/or an intermediate phenotype. Differences between patient samples reflecting stage of disorder, dietary patterns, medication use, and drug abuse are possible modifiers of FA, contributing to the heterogeneity in findings concerning FA in schizophrenia patients.Key words: Schizophrenia, FA (fatty acid), AA (arachidonic acid), NA (nervonic acid), endophenotype, familial 相似文献
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Harpreet S. Bajaj MD Itamar Raz MD Ofri Mosenzon MD Sabina A. Murphy MPH Aliza Rozenberg MA Ilan Yanuv MSc Deepak L. Bhatt MD Lawrence A. Leiter MD Darren K. McGuire MD John P. H. Wilding MD Ingrid A. M. Gause-Nilsson MD Marc S. Sabatine MD Stephen D. Wiviott MD Avivit Cahn MD 《Diabetes, obesity & metabolism》2020,22(7):1122-1131
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Deborah A. Cahn Ann C. Marcotte Robert A. Sten James E. Arruda Natacha A. Akshoomoff Isabell C. Leshko 《The Clinical neuropsychologist》2013,27(4):397-406
Abstract The Boston Qualitative Scoring System (BQSS) for the Rey-Osterrieth Complex Figure (ROCF) was utilized to examine the qualitative features of ROCF performance of children with Attention Deficit Hyperactivity Disorder (ADHD). Thirty-nine children with ADHD were compared to age-matched controls (n = 39) on their reproduction of the ROCF. ADHD children performed more poorly than did control children on measures of attention to detail, expansion, accuracy, and neatness. Sensitivity and specificity of individual BQSS measures for discriminating ADHD from control subjects were determined, and a logistic regression model was derived, yielding an overall sensitivity of 64% and specificity of 97% for the classification of ADHD. Eighty-one percent of all children were correctly classified. Cross-validation of this model on an independent sample of ADHD and control subjects revealed good predictive accuracy. These findings suggest that the BQSS may be a useful measure in the neuropsychological evaluation of children with suspected ADHD. 相似文献
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M Sension P Cahn P Domingo S Hodder M Opsomer E Lathouwers T Van de Casteele F Tomaka 《HIV medicine》2013,14(7):437-444
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Avivit Cahn MD Itamar Raz MD Marc Bonaca MD Ofri Mosenzon MD Sabina A. Murphy MPH Ilan Yanuv MSc Aliza Rozenberg MA John P. H. Wilding MD Deepak L. Bhatt MD Darren K. McGuire MD Ingrid A. M. Gause-Nilsson MD Martin Fredriksson MD Peter A. Johansson MSc Gyorgy Jermendy MD Samy Hadjadj MD Anna Maria Langkilde MD Marc S. Sabatine MD Stephen D. Wiviott MD Lawrence A. Leiter MD 《Diabetes, obesity & metabolism》2020,22(8):1357-1368