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排序方式: 共有382条查询结果,搜索用时 62 毫秒
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Cristina Mei Joanna Fitzsimons Nicholas Allen Mario Alvarez‐Jimenez Günter Paul Amminger Vivienne Browne Mary Cannon Maryann Davis Barbara Dooley Ian B. Hickie Srividya Iyer Ein Killackey Ashok Malla Ian Manion Steve Mathias Kerryn Pennell Rosemary Purcell Debra Rickwood Swaran P. Singh Stephen J. Wood Alison Yung Patrick D. McGorry 《Early intervention in psychiatry》2020,14(1):3-13
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Simon M Rice Joanne Goodall Sarah E Hetrick Alexandra G Parker Tamsyn Gilbertson G. Paul Amminger Christopher G Davey Patrick D McGorry John Gleeson Mario Alvarez-Jimenez 《Journal of medical Internet research》2014,16(9)
Background
Major depression accounts for the greatest burden of all diseases globally. The peak onset of depression occurs between adolescence and young adulthood, and for many individuals, depression displays a relapse-remitting and increasingly severe course. Given this, the development of cost-effective, acceptable, and population-focused interventions for depression is critical. A number of online interventions (both prevention and acute phase) have been tested in young people with promising results. As these interventions differ in content, clinician input, and modality, it is important to identify key features (or unhelpful functions) associated with treatment outcomes.Objective
A systematic review of the research literature was undertaken. The review was designed to focus on two aspects of online intervention: (1) standard approaches evaluating online intervention content in randomized controlled designs (Section 1), and (2) second-generation online interventions and services using social networking (eg, social networking sites and online support groups) in any type of research design (Section 2).Methods
Two specific literature searches were undertaken. There was no date range specified. The Section 1 search, which focused on randomized controlled trials, included only young people (12-25 years) and yielded 101 study abstracts, of which 15 met the review inclusion criteria. The Section 2 search, which included all study design types and was not restricted in terms of age, yielded 358 abstracts, of which 22 studies met the inclusion criteria. Information about the studies and their findings were extracted and tabulated for review.Results
The 15 studies identified in Section 1 described 10 trials testing eight different online interventions, all of which were based on a cognitive behavioral framework. All but one of the eight identified studies reported positive results; however, only five of the 15 studies used blinded interviewer administered outcomes with most trials using self-report data. Studies varied significantly in presentation of intervention content, treatment dose, and dropout. Only two studies included moderator or clinician input. Results for Section 2 were less consistent. None of the Section 2 studies reported controlled or randomized designs. With the exception of four studies, all included participants were younger than 25 years of age. Eight of the 16 social networking studies reported positive results for depression-related outcomes. The remaining studies were either mixed or negative. Findings for online support groups tended to be more positive; however, noteworthy risks were identified.Conclusions
Online interventions with a broad cognitive behavioral focus appear to be promising in reducing depression symptomology in young people. Further research is required into the effectiveness of online interventions delivering cognitive behavioral subcomponents, such as problem-solving therapy. Evidence for the use of social networking is less compelling, although limited by a lack of well-designed studies and social networking interventions. A range of future social networking therapeutic opportunities are highlighted. 相似文献6.
Tsutomu Takahashi Stephen J. Wood Bridget Soulsby Ryoichiro Tanino Michael T.H. Wong Patrick D. McGorry Michio Suzuki Dennis Velakoulis Christos Pantelis 《Progress in neuro-psychopharmacology & biological psychiatry》2009
Volume reductions of the insular cortex have been described in schizophrenia, but it remains unclear whether other psychotic disorders such as affective psychosis also exhibit insular cortex abnormalities. In this study, we used magnetic resonance imaging to investigate the gray matter volume of the anterior (short) and posterior (long) insular cortices in 162 first-episode patients with various psychotic disorders (46 schizophrenia, 57 schizophreniform disorder, 34 affective psychosis, and 25 other psychoses) and 62 age- and gender-matched healthy comparison subjects. Patients with schizophrenia showed bilateral volume reduction of the anterior and posterior insular cortices compared with controls, but the remaining first-episode psychosis subgroups had normal insular volumes. The volumes of these insular subregions were significantly smaller in schizophrenia patients than in patients with schizophreniform disorder or affective psychoses. There was no association between the insular cortex volume and daily dosage or type of antipsychotic medication in any patient group. These findings suggest that the widespread volume reduction of the insular cortex is specific to established schizophrenia, implicating its role in the neurobiology of clinical characteristics associated with schizophrenia. 相似文献
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Wannan Cassandra M. J. Bartholomeusz Cali F. Pantelis Christos Di Biase Maria A. Syeda Warda T. Chakravarty M. Mallar Bousman Chad A. Everall Ian P. McGorry Patrick D. Zalesky Andrew Cropley Vanessa L. 《European archives of psychiatry and clinical neuroscience》2022,272(6):971-983
European Archives of Psychiatry and Clinical Neuroscience - Episodic memory ability relies on hippocampal-prefrontal connectivity. However, few studies have examined relationships between memory... 相似文献
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