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排序方式: 共有259条查询结果,搜索用时 62 毫秒
1.
Frontera Jennifer Mainali Shraddha Fink Ericka L. Robertson Courtney L. Schober Michelle Ziai Wendy Menon David Kochanek Patrick M. Suarez Jose I. Helbok Raimund McNett Molly Chou Sherry H.-Y. 《Neurocritical care》2020,33(1):25-34
Neurocritical Care - As the COVID-19 pandemic developed, reports of neurological dysfunctions spanning the central and peripheral nervous systems have emerged. The spectrum of acute neurological... 相似文献
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Frontera Jennifer A. Bhatt Prachi Lalchan Rebecca Yaghi Shadi Ahuja Tania Papadopoulos John Joset Danielle 《Journal of thrombosis and thrombolysis》2020,49(1):121-131
Journal of Thrombosis and Thrombolysis - Andexanet-alpha is a specific reversal agent for direct factor Xa inhibitors (dFXaI). We aimed to project utilization rates and cost of andexanet for... 相似文献
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Moheet Asma M. Shapshak Angela H. Brissie Megan A. Abulhasan Yasser B. Brophy Gretchen M. Frontera Jennifer Hall Wiley R. John Sayona Kalanuria Atul A. Kumar Abhay Lele Abhijit V. Mainali Shraddha May Casey C. Mayer Stephan A. McCredie Victoria Silva Gisele S. Singh Jeffrey M. Steinberg Alexis Sung Gene Tesoro Eljim P. Yakhkind Aleksandra 《Neurocritical care》2020,33(1):13-19
Neurocritical Care - 相似文献
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José Miguel Baena-Díez Isaac Subirana Rafael Ramos Agustín Gómez de la Cámara Roberto Elosua Joan Vila Alejandro Marín-Ibáñez María Jesús Guembe Fernando Rigo María José Tormo-Díaz Conchi Moreno-Iribas Joan Josep Cabré Antonio Segura José Lapetra Miquel Quesada María José Medrano Paulino González-Diego Guillem Frontera Jaume Marrugat 《Revista espa?ola de cardiología》2018,71(4):274-282
Introduction and objectives
To assess the validity of the original low-risk SCORE function without and with high-density lipoprotein cholesterol and SCORE calibrated to the Spanish population.Methods
Pooled analysis with individual data from 12 Spanish population-based cohort studies. We included 30 919 individuals aged 40 to 64 years with no history of cardiovascular disease at baseline, who were followed up for 10 years for the causes of death included in the SCORE project. The validity of the risk functions was analyzed with the area under the ROC curve (discrimination) and the Hosmer-Lemeshow test (calibration), respectively.Results
Follow-up comprised 286 105 persons/y. Ten-year cardiovascular mortality was 0.6%. The ratio between estimated/observed cases ranged from 9.1, 6.5, and 9.1 in men and 3.3, 1.3, and 1.9 in women with original low-risk SCORE risk function without and with high-density lipoprotein cholesterol and calibrated SCORE, respectively; differences were statistically significant with the Hosmer-Lemeshow test between predicted and observed mortality with SCORE (P < .001 in both sexes and with all functions). The area under the ROC curve with the original SCORE was 0.68 in men and 0.69 in women.Conclusions
All versions of the SCORE functions available in Spain significantly overestimate the cardiovascular mortality observed in the Spanish population. Despite the acceptable discrimination capacity, prediction of the number of fatal cardiovascular events (calibration) was significantly inaccurate.Full English text available from:www.revespcardiol.org/en 相似文献7.
Arcangeli ML Frontera V Bardin F Obrados E Adams S Chabannon C Schiff C Mancini SJ Adams RH Aurrand-Lions M 《Blood》2011,118(17):4609-4619
In adult mammals, hematopoietic stem cells (HSCs) reside in the bone marrow (BM) and are maintained in a quiescent and undifferentiated state through adhesive interactions with specialized microenvironmental niches. Although junctional adhesion molecule-C (JAM-C) is expressed by HSCs, its function in adult hematopoiesis remains elusive. Here, we show that HSCs adhere to JAM-B expressed by BM stromal cells in a JAM-C dependent manner. The interaction regulates the interplay between HSCs and BM stromal cells as illustrated by the decreased pool of quiescent HSCs observed in jam-b deficient mice. We further show that this is probably because of alterations of BM stromal compartments and changes in SDF-1α BM content in jam-b(-/-) mice, suggesting that JAM-B is an active player in the maintenance of the BM stromal microenvironment. 相似文献
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Snehasish Thakur Michael G. B. Drew Antonio Franconetti Antonio Frontera Shouvik Chattopadhyay 《RSC advances》2019,9(60):35165
A dinuclear vanadium(v) complex, (μ-O)2[V(O)(L)]2, [where HL = 2-methoxy-6-((2-(2-hydroxyethylamino)ethylimino)methyl)phenol] has been synthesized and characterized by spectral and elemental analysis. A single crystal X-ray diffraction study confirms it structure. Two different conformations, stabilized via either intra- or inter-dinuclear hydrogen bonding interactions, co-exist in the solid-state structure. The energies of these intra- or inter-dinuclear hydrogen bonding interactions have been estimated by Density functional theory (DFT) calculations. A ‘Non-covalent interaction’ (NCI) plot has also been used to characterize these interactions.Two different hydrogen bonded conformers coexist in a synthesized dinuclear oxovanadium(v) Schiff base. Density functional theory (DFT) calculations were utilized to calculate the energies involved in two different conformers. 相似文献
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Kathleen Puntillo Judith Eve Nelson David Weissman Randall Curtis Stefanie Weiss Jennifer Frontera Michelle Gabriel Ross Hays Dana Lustbader Anne Mosenthal Colleen Mulkerin Daniel Ray Rick Bassett Renee Boss Karen Brasel Margaret Campbell 《Intensive care medicine》2014,40(2):235-248