全文获取类型
收费全文 | 7589篇 |
免费 | 469篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 92篇 |
儿科学 | 211篇 |
妇产科学 | 148篇 |
基础医学 | 1032篇 |
口腔科学 | 612篇 |
临床医学 | 606篇 |
内科学 | 1530篇 |
皮肤病学 | 204篇 |
神经病学 | 567篇 |
特种医学 | 175篇 |
外科学 | 1005篇 |
综合类 | 37篇 |
一般理论 | 2篇 |
预防医学 | 680篇 |
眼科学 | 185篇 |
药学 | 639篇 |
中国医学 | 57篇 |
肿瘤学 | 307篇 |
出版年
2023年 | 64篇 |
2022年 | 94篇 |
2021年 | 277篇 |
2020年 | 202篇 |
2019年 | 238篇 |
2018年 | 324篇 |
2017年 | 193篇 |
2016年 | 235篇 |
2015年 | 300篇 |
2014年 | 397篇 |
2013年 | 424篇 |
2012年 | 603篇 |
2011年 | 707篇 |
2010年 | 335篇 |
2009年 | 259篇 |
2008年 | 426篇 |
2007年 | 464篇 |
2006年 | 362篇 |
2005年 | 361篇 |
2004年 | 269篇 |
2003年 | 232篇 |
2002年 | 199篇 |
2001年 | 127篇 |
2000年 | 120篇 |
1999年 | 114篇 |
1998年 | 38篇 |
1997年 | 31篇 |
1996年 | 32篇 |
1995年 | 27篇 |
1994年 | 22篇 |
1993年 | 12篇 |
1992年 | 63篇 |
1991年 | 68篇 |
1990年 | 37篇 |
1989年 | 52篇 |
1988年 | 42篇 |
1987年 | 29篇 |
1986年 | 34篇 |
1985年 | 30篇 |
1984年 | 23篇 |
1983年 | 12篇 |
1981年 | 12篇 |
1980年 | 21篇 |
1979年 | 24篇 |
1978年 | 21篇 |
1977年 | 14篇 |
1976年 | 12篇 |
1975年 | 11篇 |
1974年 | 16篇 |
1973年 | 10篇 |
排序方式: 共有8089条查询结果,搜索用时 15 毫秒
1.
Lucas F Soveral Gabriela G Korczaguin Pedro S Schmidt Isabel S Nunes Camilo Fernandes Carlos R Z rate-Blad s 《World journal of gastroenterology : WJG》2022,28(33):4762-4772
Fecal microbiota transplantation (FMT) is a successful method for treating recurrent Clostridioides difficile (C. difficile) infection (rCDI) with around 90% efficacy. Due to the relative simplicity of this approach, it is being widely used and currently, thousands of patients have been treated with FMT worldwide. Nonetheless, the mechanisms underlying its effects are just beginning to be understood. Data indicate that FMT effectiveness is due to a combination of microbiological direct mechanisms against C. difficile, but also through indirect mechanisms including the production of microbiota-derived metabolites as secondary bile acids and short chain fatty acids. Moreover, the modulation of the strong inflammatory response triggered by C. difficile after FMT seems to rely on a pivotal role of regulatory T cells, which would be responsible for the reduction of several cells and soluble inflammatory mediators, ensuing normalization of the intestinal mucosal immune system. In this minireview, we analyze recent advances in these immunological aspects associated with the efficacy of FMT. 相似文献
2.
Zancanella Edilson do Prado Lucila Fernandes de Carvalho Luciane Bizari Machado Júnior Almiro J. Crespo Agrício Nubiato do Prado Gilmar Fernandes 《Sleep & breathing》2022,26(1):117-123
Sleep and Breathing - There are no studies comparing tests performed at home with those carried out in the laboratory, using the same device. The only studies that have been performed... 相似文献
3.
Marc Evans MD Susanne Engberg MD Mads Faurby MSc João Diogo Da Rocha Fernandes MSc Pollyanna Hudson MSc William Polonsky PhD 《Diabetes, obesity & metabolism》2022,24(3):377-390
We designed a systematic literature review to identify available evidence on adherence to and persistence with antidiabetic medication in people with type 2 diabetes (T2D). Electronic screening and congress searches identified real-world noninterventional studies (published between 2010 and October 2020) reporting estimates of adherence to and persistence with antidiabetic medication in adults with T2D, and associations with glycaemic control, microvascular and/or macrovascular complications, hospitalizations and healthcare costs. Ninety-two relevant studies were identified, the majority of which were retrospective and reported US data. The proportions of patients considered adherent (median [range] 51.2% [9.4%-84.3%]) or persistent (median [range] 47.7% [16.9%-94.0%]) varied widely across studies. Multiple studies reported an association between greater adherence/persistence and greater reductions in glycated haemoglobin levels. Better adherence/persistence was associated with fewer microvascular and/or macrovascular outcomes, although there was little consistency across studies in terms of which outcomes were improved. More adherent and more persistent patients were typically less likely to be hospitalized or to have emergency department visits/admissions and spent fewer days in hospital annually than less adherent/persistent patients. Greater adherence and persistence were generally associated with lower hospitalization costs, higher pharmacy costs and lower or budget-neutral total healthcare costs compared with lower adherence/persistence. In conclusion, better adherence and persistence in people with T2D is associated with lower rates of microvascular and/or macrovascular outcomes and inpatient hospitalization, and lower or budget-neutral total healthcare expenditure. Education and treatment strategies to address suboptimal adherence and persistence are needed to improve clinical and economic outcomes. 相似文献
4.
5.
de Morais Pollyana C. V. Gama Allyne F. Fernandes Gabrielle M. Oliveira Andre H. B. Lima Marcielly F. B. dos Santos Felipe R. Martins Davi A. Nascimento Ronaldo F. Cavalcante Rivelino M. 《Bulletin of environmental contamination and toxicology》2019,102(1):66-76
Bulletin of Environmental Contamination and Toxicology - This work describes the development of an analytical protocol combining cleanup by liquid–solid extraction and GC–MS for the... 相似文献
6.
7.
8.
9.
10.
Flávia Silva Arbex Borim Tiago da Silva Alexandre Anita Liberalesso Neri Roberta de Oliveira Máximo Marcela Fernandes Silva Cesar de Oliveira 《Journal of the American Medical Directors Association》2019,20(1):47-52