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Eubanks August Coulibaly Bakary Dembélé Keita Bintou Anoma Camille DAH Ter Tiero Elias Mensah Ephrem Maradan Gwenaëlle Bourrelly Michel Mora Marion Riegel Lucas Rojas Castro Daniela Yaya Issifou Spire Bruno Laurent Christian Sagaon-Teyssier Luis 《AIDS and behavior》2022,26(11):3524-3537
AIDS and Behavior - We investigated the rate and predictors of ineffective HIV protection in men who have sex with men (MSM) taking pre-exposure prophylaxis (PrEP) in a prospective cohort study... 相似文献
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Jacquemin L. Bourrelly N. Roth O. Wiedemann J.-Y. Le Bouar R. Levy J. Monassier J.-P. 《Annales de cardiologie et d'angeiologie》2010,59(3):119-124
Aims of the study
The study evaluated in-hospital and long-term outcome of patients less than 50 years old with myocardial infarction within 12 hours after symptom onset treated by coronary angioplasty.Patients and method
This is a retrospective study with survival analysis by Kaplan-Meier method in patients included from December 2003 to February 2008.Results
We included 93 patients aged 42,8 ± 5,2 years old with smoking estimated at 27,7 ± 12,7 pack-years. Thirty-one patients (33,3%) were dyslipidemic and 36 patients had family history of coronary artery disease. Thirty patients (32,3%) had an anterior myocardial infarction and four patients (4.4%) had Killip greater than 2. Coronary angioplasty was performed within 4.5 ± 3.0 hours after symptom onset with TIMI 3 final flow in the culprit vessel in 96.8%. One patient died from cardiogenic shock. With a follow-up of 85 patients during 20.0 ± 15.6 months, the survival without death was 98.2% and survival without major cardiac complication was 87.9% at 24 months. Seventy-two patients (85.7%) were taking a betablocker, 81 patients (96.4%) aspirin, 75 patients (89.3%) a statin and 64 patients (76.2%) an angiotensin-converting inhibitor. Only 50 patients (58.8%) were nonsmokers.Conclusion
Thus, young smokers with acute MI treated by coronary angioplasty have a good prognosis during in-hospital stay and long-term outcome. Secondary medical treatment prevention is well followed but there is a low rate of smoking cessation. 相似文献3.
Brunet P Bourrelly M Mundler O Bouvier C Faure V Opris A Bouchouareb D Indreies M Ramananarivo P Dussol B Berland Y 《Néphrologie & thérapeutique》2008,4(3):196-201
The treatment of a patient with 131I at activity over 740 mega Becquerel (MBq) must be performed in a nuclear medicine department. Isolation is stopped if the patient radiation level is less than 20 muSv/hour at one meter. As regards patients with chronic renal failure treated with hemodialysis (HD), the first HD session will eliminate the major part of the radioactivity. French regulations do not give definite recommendations for this session. However, it imposes to collect liquid and solid wastes contaminated by radioactivity. Thus, it seems necessary to collect dialysate and solid wastes and to stock them in a room dedicated to radiation decay. The risk for dialysis staff is to be contaminated by an accidental ingestion of a biologic fluid from the patient. The usual protection barriers used during the HD session are sufficient: mask, gloves, overgarments, cap. There is no risk linked to external exposure to radiations. The maximal theoretical dose received by the staff during the session is 65 muSv, while annual maximal dose for public exposed to radiations is 1000 muSv. Although the dosimetric follow-up of dialysis staff is not mandatory, the nuclear medicine department of Marseille University Hospital has decided to do it in an information perspective. The session is performed in the presence of a radiation safety technician who gives film badges and active dosimeters to the dialysis staff. He reports the dialysis staff to the nuclear safety agency (Autorité de s?reté nucléaire). 相似文献
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Guillet B Quentin P Waultier S Bourrelly M Pisano P Mundler O 《Journal of nuclear medicine technology》2005,33(3):175-179
OBJECTIVE: The use of 18F-FDG for clinical PET studies increases technologist radiation dose exposure because of the higher gamma-radiation energy of this isotope than of other conventional medical gamma-radiation-emitting isotopes. Therefore, 18F-FDG imaging necessitates stronger radiation protection requirements. The aims of this study were to assess technologist whole-body and extremity exposure in our PET department and to evaluate the efficiency of our radiation protection devices (homemade syringe drawing device, semiautomated injector, and video tracking of patients). METHODS: Radiation dose assessment was performed for monodose as well as for multidose 18F-FDG packaging with both LiF thermoluminescence dosimeters (TLD) and electronic personal dosimeters (ED) during 5 successive 18F-FDG PET steps (from syringe filling to patient departure). RESULTS: The mean +/- SD total effective doses received by technologists (n = 50) during all of the working steps were 3.24 +/- 2.1 and 3.01 +/- 1.4 microSv, respectively, as measured with ED and TLD (345 +/- 84 MBq injected). These values were confirmed by daily TLD technologist whole-body dose measurements (2.98 +/- 1.8 microSv; 294 +/- 78 MBq injected; n = 48). Finger irradiation doses during preparation of single 18F-FDG syringes were 204.9 +/- 24 and 198.4 +/- 23 microSv with multidose vials (345 +/- 93 MBq injected) and 127.3 +/- 76 and 55.9 +/- 47 microSv with monodose vials (302 +/- 43 MBq injected) for the right hand and the left hand, respectively. The protection afforded by the semiautomated injector, estimated as the ratio of the doses received by TLD placed on the syringe shield and on the external face of the injector, was near 2,000. CONCLUSION: These results showed that technologist radiation doses in our PET department were lower than those reported in the literature. This finding may be explained by the use of a homemade syringe drawing device, a semiautomated injector, and patient video tracking, allowing a shorter duration of contact between the technologist and the patient. Extrapolation of these results to an annual dose (4 patients per day per technologist) revealed that the annual extrapolated exposure values remained under the authorized limits for workers classified to work in a radioactivity-controlled area. 相似文献
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Koya Ariyoshi Stuart Bloor Paul D. Bieniasz Michel Bourrelly Russell Foxall Jonathan N. Weber 《Journal of medical virology》1994,43(1):28-32
A simple and rapid assay for the quantification of infectious HIV-1 in plasma was developed using short-term culture and DNA PCR. This method, called culture PCR, allows detection and quantification of infectious HIV-1 viraemia within 48 hours, and measures the number of infectious cell-free HIV-1 particles, expressed as culture PCR infectious doses (CPID/ml). 42 HIV infected subjects were assessed by this method. The titres obtained by CPID closely correlated with CD4+ count and clinical status. CPID titres had significant correlation with infectious virus titre determined by conventional limiting dilution tissue-culture methods. This culture-PCR technique permits rapid assessment of infectious plasma viraemia, and is comparable to longer culture based assay methods. © 1994 Wiley-Liss, Inc. 相似文献
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Interest in HIV pre‐exposure prophylaxis in men who have sex with men in West Africa (CohMSM ANRS 12324 – Expertise France) 下载免费PDF全文
Pierre‐julien Coulaud Luis Sagaon‐Teyssier Bakridine M'madi Mrenda Gwenaëlle Maradan Marion Mora Michel Bourrelly Bintou Dembélé Keita Abdoul Aziz Keita Camille Anoma Stéphane‐Alain Babo Yoro Ter Tiero Elias Dah Christian Coulibaly Ephrem Mensah Selom Agbomadji Adeline Bernier Clotilde Couderc Christian Laurent Bruno Spire The CohMSM Study Group 《Tropical medicine & international health : TM & IH》2018,23(10):1084-1091
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We studied the effect of static pitch body tilts on the perception of self-motion direction induced by a visual stimulus. Subjects were seated in front of a screen on which was projected a 3D cluster of moving dots visually simulating a forward motion of the observer with upward or downward directional biases (relative to a true earth horizontal direction). The subjects were tilted at various angles relative to gravity and were asked to estimate the direction of the perceived motion (nose-up, as during take-off or nose-down, as during landing). The data showed that body orientation proportionally affected the amount of error in the reported perceived direction (by 40% of body tilt magnitude in a range of ±20°) and these errors were systematically recorded in the direction of body tilt. As a consequence, a same visual stimulus was differently interpreted depending on body orientation. While the subjects were required to perform the task in a geocentric reference frame (i.e., relative to a gravity-related direction), they were obviously influenced by egocentric references. These results suggest that the perception of self-motion is not elaborated within an exclusive reference frame (either egocentric or geocentric) but rather results from the combined influence of both. 相似文献
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Bourrelly A Bringoux L Vercher JL 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2009,198(1):19-28
We investigated the influence of gaze elevation on judging the possibility of passing under high obstacles during pitch body
tilts, while stationary, in absence of allocentric cues. Specifically, we aimed at studying the influence of egocentric references
upon geocentric judgements. Seated subjects, orientated at various body orientations, were asked to perceptually estimate
the possibility of passing under a projected horizontal line while keeping their gaze on a fixation target and imagining a
horizontal body displacement. The results showed a global overestimation of the possibility of passing under the line, and
confirmed the influence of body orientation reported by Bringoux et al. (Exp Brain Res 185(4):673–680, 2008). More strikingly, a linear influence of gaze elevation was found on perceptual estimates. Precisely, downward eye elevation
yielded increased overestimations, and conversely upward gaze elevation yielded decreased overestimations. Furthermore, body
and gaze orientation effects were independent and combined additively to yield a global egocentric influence with a weight
of 45 and 54%, respectively. Overall, our data suggest that multiple egocentric references can jointly affect the estimated
possibility of passing under high obstacles. These results are discussed in terms of “interpenetrability” between geocentric
and egocentric reference frames and clearly demonstrate that gaze elevation is involved, as body orientation, in geocentric
spatial localization. 相似文献