正常范围甲状腺激素水平与冠状动脉Gensini评分的相关性分析

Abstrat：Objective To study the correlation between normal level of thyroid hormone and gensini coronary scoring system．Methods 233 patients who were treated with CAG and diagnosed of patients with coronary heart disease were divided into 4 groups based on gensini coronary scoring system ,all the patients were determined kinds of index which include triiodothyronine(T3),thyronine(T4),free thyronine(FT4), free triiodothyronine (FT3), thyroid stimulating hormone (TSH) and correlation between thyroid hormone level and gensini coronary scoring system was studied by Spearman correlation analysis and Multiple regression analysis.Results No significant difference was found in the levels of triiodothyronine(T3),thyronine(T4),freethyronine(FT4),Cholesterol(CHO)andTriglyceride(TG) between the 4 groups(P>0．05).FT3 and HDL-C decreased with the increase of the degree of coronary artery lesions（P<0.01）, AGE and LDL-C increased with the increase of the degreeof coronary artery lesions(P<0.05),there was statistical significance.Negative linear correlation was found between the gensini coronary scoring system and FT3、HDL-c,was positively correlated with age and LDL-C .both the index Was independently correlated to Gensini integral.Conclusion the lower level of FT3 is an indepent risk factor for lesion severity of CHD．      

腹膜后肿瘤的手术原则和经路

腹膜后肿瘤少见,又无特殊症状,因此就医晚,且肿瘤大,多侵及邻近器官、血管、临床很难准确判断其大小和准确部位.外科手术切除是本病的基本治疗方法. 一、手术适应证及禁忌证手术适应证: (一)凡怀疑腹膜后肿瘤,不论良性、恶性,不论体积大小,只要没有禁忌证者,皆应手术探查. (二)探查时未能切除肿瘤,探查后经放射治疗或     

Expression of Nuclear Factor-κB in Mouse Uterus during Peri-implantation

To investigate the expression of the subunit p65 of NF-κB and inhibitor kappa B alpha (IκBα) in mouse uterus during peri-implantation, thereby investigating whether transient activation of nuclear factor-κB (NF-κB) takes place during embryo implantation in mice. Immunohistochemical technique was used to examine the expression and localization of p65 in endometrium or deciduas, and Western blot analysis was employed to detect the levels of IκBα protein in mouse endometrium or deciduas. P65 protein was detected in stromal cells, epithelial cells of endometrium as well as in myometrium. Staining was predominately seen in the cytoplasm of the cells. Staining intensity for p65 was stronger in the epithelial compartment than the stromal compartment and myometrium. Staining intensity increased slightly during pregnancy, and it reached a high level on pregnancy day 5 and day 8. In contrast to p65, the level of IκBα protein was lowest on pregnancy day 5 in all groups. Our results suggested that NF-κB may regulate embryo implantation by its transient activation in mice.     

类固醇激素与年龄有关的变化

类固醇激素的产生是以多变性为其特征。如皮质类固醇的产生在一天24小时内有变化,随月经周期而每月变化,以及在一生中各个时期如青春期、更年期、男性更年期、肾上腺激素初现期、肾上腺激素停止期亦均有变化等。类固醇激素全部以类固醇核为基础,主要从胆固醇衍生而出。不同的类固醇分子——皮质类固醇、雄激素、雌激素和孕酮,其区别在于不同侧链的数、性质和位置,而有关类固醇环结构中双键位置的变化则相对较     

药铜宫内节育器抗生育作用的实验研究

以雌性家兔交配后生殖道内精子数及其活率影响为指标，观察比较了复合型药铜宫内节育器（ＬＮＧ＿Ｃｕ－ＩＵＤ）与含铜、含孕激素宫内节育器（Ｃｕ－ＩＵＤ、ＬＮＧ－ＩＵＤ）的抗生育作用。结果表明，３种ＩＵＤｓ均能明显减少子宫和输卵管中精子数，并降低其活率，其中以药铜宫内节育器最为显著，放置ＬＮＧＣｕ－ＩＵＤ、Ｃｕ－ＩＵＤ、ＬＮＧ－ＩＵＤdisplay structure     

乳房良性肿块的药物治疗

乳房疾病的主要临床征象有三:肿块、乳头溢液、疼痛.除恶性肿瘤外,乳房许多良性疾病可以形成乳房肿块.这些疾病包括:①炎症,⑦寄生虫,③乳腺结